Expiratory flow limitation under moderate hypobaric hypoxia does not influence ventilatory responses during incremental running in endurance runners
Expiratory flow limitation under moderate hypobaric hypoxia does not influence ventilatory responses during incremental running in endurance runners
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DOI：
10.14814/phy2.13996
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发表时间：
2019-02-01
影响因子：
2.5
通讯作者：
Nishiyasu, Takeshi
中科院分区：
文献类型：
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作者：
Cao, Yinhang;Ichikawa, Yuhei;Nishiyasu, Takeshi
我们测试了在相当于海拔2500米的中等低压低氧环境中，耐力运动员是否出现呼气流量受限(EFL)，如果是，EFL是否抑制了峰值通气量(VEPeak)，从而加剧了低氧诱导的峰值摄氧量(VO2Peak)的下降。17名年轻男子耐力跑步者分别在低压低氧(560 Mm Hg)和常压常氧(760 Mm Hg)条件下进行递增力竭跑。测量摄氧量(VO2)、每分钟通气量(VE)、动脉血氧饱和度(SpO(2))和操作肺容量。在接受测试的跑步者中，35%的跑步者在低压低氧条件下出现了EFL(EFL组，n=6)，而其余的跑步者(非EFL组，n=11)没有出现EFL。EFL组和非EFL组在任一状态下的VO2峰和VO2峰均无差异。EFL组和非EFL组从常压常压到低压低氧的VO2峰值(-18+/-6比-16+/-6%)和VE峰值(4+/-4比2+/-4%)的百分比变化也没有差异(均P>；0.05)。在两种情况下，两组的最大跑步速度、SpO(2)或操作肺容量均无差异。这些结果表明，在常用于高原训练的中度低压低氧(海拔2500米)下，与35%的耐力运动员相似，他们可能出现EFL，但他们在极量运动中的呼吸和代谢反应与没有EFL的人相似。
We tested whether expiratory flow limitation (EFL) occurs in endurance athletes in a moderately hypobaric hypoxic environment equivalent to 2500 m above sea level and, if so, whether EFL inhibits peak ventilation (VEpeak), thereby exacerbating the hypoxia-induced reduction in peak oxygen uptake (VO2peak). Seventeen young male endurance runners performed incremental exhaustive running on separate days under hypobaric hypoxic (560 mmHg) and normobaric normoxic (760 mmHg) conditions. Oxygen uptake (VO2), minute ventilation (VE), arterial O-2 saturation (SpO(2)), and operating lung volume were measured throughout the incremental exercise. Among the runners tested, 35% exhibited EFL (EFL group, n = 6) in the hypobaric hypoxic condition, whereas the rest did not (Non-EFL group, n = 11). There were no differences between the EFL and Non-EFL groups for VEpeak and VO2peak under either condition. Percent changes in VEpeak (4 +/- 4 vs. 2 +/- 4%) and VO2peak (-18 +/- 6 vs. -16 +/- 6%) from normobaric normoxia to hypobaric hypoxia also did not differ between the EFL and Non-EFL groups (all P > 0.05). No differences in maximal running velocity, SpO(2), or operating lung volume were detected between the two groups under either condition. These results suggest that under the moderate hypobaric hypoxia (2500 m above sea level) frequently used for high-attitude training, similar to 35% of endurance athletes may exhibit EFL, but their ventilatory and metabolic responses during maximal exercise are similar to those who do not exhibit EFL.