Low-load/high-repetition elastic band resistance training in patients with COPD: a randomized, controlled, multicenter trial
Low-load/high-repetition elastic band resistance training in patients with COPD: a randomized, controlled, multicenter trial
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DOI：
10.1111/crj.12141
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发表时间：
2015-07-01
影响因子：
1.7
通讯作者：
Wadell, Karin
中科院分区：
文献类型：
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作者：
Nyberg, Andre;Lindstrom, Britta;Wadell, Karin
背景和目的：推荐高重复阻力训练（RT）来提高健康成人的外周肌肉耐力；然而，这种设计的RT对慢性阻塞性肺疾病（COPD）患者的运动能力和健康相关生活质量（HRQOL）的影响尚不清楚。本研究旨在探讨低负荷/高重复弹性带RT是否能改善COPD患者的功能能力、肌肉功能、耐力周期能力或HRQOL。方法采用隐蔽分配、盲法结局评价和意向治疗分析，构建前瞻性、随机、对照、多中心试验。共纳入44例中度至极重度COPD患者（第一秒用力呼气量，预测44.6%）。患者被随机分为两组，实验组接受8周的RT治疗（3次/周），并结合患者教育（4次），对照组接受单独的患者教育。结果在后测中，实验组在6 min步行测试[平均差值（95%置信区间）]:34m（14-54）和6 min钉板环测试[20环（3-37）]上组间差异明显。在慢性呼吸道疾病问卷调查中，两组间无差异[0.1(-0.2至0.4)]。在次要结果方面，实验组在上肢耐力、肌肉功能和抑郁方面均优于实验组，但在耐力循环能力和HRQOL方面各组间无差异。结论rt治疗可提高中重度COPD患者的功能能力和肌肉功能，但不能提高循环耐力和HRQOL。
Background and AimsHigh-repetitive resistance training (RT) is recommended to increase peripheral muscular endurance in healthy adults; however, the effects of RT with this design on exercise capacity and health-related quality of life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD) is unknown. The study aimed to investigate if low-load/high-repetition elastic band RT could improve functional capacity, muscular function, endurance cycle capacity or HRQOL in patients with COPD.MethodsA prospective, randomized, controlled, multicentre trial was constructed with concealed allocation, blinded outcome assessment and intention-to-treat analysis. A total of 44 patients with moderate-to-very-severe COPD (forced expiratory volume during the first second, 44.6% predicted) were included. Patients were randomized to either the experimental group receiving 8 weeks of RT (three sessions/week) in combination with patient education (four occasions) or the control group receiving the patient education alone.ResultsAt post-tests, the between-group differences were in favor of the experimental group on the 6-min walk test [mean difference (95% confidence interval)]: 34m (14-54) and the 6-min pegboard and ring test [20 rings (3-37)]. No difference between groups was found on the chronic respiratory disease questionnaire [0.1 (-0.2 to 0.4)]. On secondary outcomes, results were in favor of the experimental group regarding upper extremity endurance capacity, muscular function and depression, but no difference was seen between groups on endurance cycle capacity and HRQOL.ConclusionRT can increase functional capacity and muscular function but not cycle endurance capacity and HRQOL in patients with moderate-to-severe COPD.