Virtual lesion of ventral premotor cortex impairs visual perception of biomechanically possible but not impossible actions
Virtual lesion of ventral premotor cortex impairs visual perception of biomechanically possible but not impossible actions
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DOI：
10.1080/17470910701676269
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发表时间：
2008-09-01
影响因子：
2
通讯作者：
Aglioti, Salvatore M.
中科院分区：
文献类型：
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作者：
Candidi, Matteo;Urgesi, Cosimo;Aglioti, Salvatore M.
单脉冲经颅磁刺激（TMS）研究表明，动作观察促进了运动员的皮质脊髓系统支持运动镜像的概念。重复经颅磁刺激（rTMS）腹侧前运动皮层（vPMc）损害身体动作的视觉辨别。虽然研究表明，行动观察-执行匹配系统可能只映射属于观察员的运动指令集的行动，但我们在观察生物力学上可能的和不可能的行动时证明了可比的运动和运动前促进。研究还表明，看到不可能的身体动作会激活纹状体外体区（EBA）。使用事件相关的rTMS，我们试图确定vPMc和EBA是否积极参与通过生物力学上可能或不可能的运动学及其生物力学可接受性进行的动作的视觉辨别。刺激vPMc损害了可能的行动的歧视，而保持完整的生物力学不可能的行动和生物力学的可接受性的歧视。EBA rTMS对任何类型的动作加工都没有影响，因此，vPMc对于区分实际可以执行的动作的目标是至关重要的，这表明该区域参与了目标导向动作的视觉加工。
Single-pulse transcranial magnetic stimulation (TMS) studies show that action observation facilitates the onlooker's cortico-spinal system supporting the notion of motor mirroring. Repetitive transcranial magnetic stimulation (rTMS) over ventral premotor cortex (vPMc) impairs visual discrimination of body actions. Although studies suggest that the action observation-execution matching system may map only actions that belong to the observer's motor repertoire, we demonstrated comparable motor and premotor facilitation during observation of biomechanically possible as well as impossible actions. It has also been shown that seeing impossible body movements activates the extrastriate body area (EBA). Using event-related rTMS, we sought to determine whether vPMc and EBA are actively involved in the visual discrimination of actions performed through biomechanically possible or impossible kinematics and of their biomechanical plausibility. Stimulation of vPMc impaired discrimination of possible actions while leaving intact the discrimination of biomechanically impossible actions and of biomechanical plausibility. No effect of EBA rTMS on any type of action processing was found. Thus, vPMc is crucial for discrimination of the goal of actions that can be actually performed suggesting that this area is involved in the visual processing of goal-directed actions.