Role of Oxidative Stress and Antioxidants in Thiram-induced Tibial Dyschondroplasia
Role of Oxidative Stress and Antioxidants in Thiram-induced Tibial Dyschondroplasia
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DOI：
10.29261/pakvetj/2020.094
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Hui Zhang
中科院分区：
文献类型：
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作者：
Bingxian Liu;Ying Li;Khalid Mehmood;Fazul Nabi;Shakeel Ahmed;Tauseef-ur-Rehman;Mehwish Faheem;Mariyam Ashraf;Zhaoxin Tang;Hui Zhang
Tetramethyl thiuram disulfide (thiram) is an important dithiocarbamate bactericide; it has been widely used for the control of various diseases in fruits, vegetables, seeds and food grains. However, it also causes environmental pollution problems and poses a threat to human health to a certain extent. Thiram induces tibial dyschondroplasia (TD) by causing oxidative stress and antioxidants imbalance in tibial growth plate in poultry. TD is a skeletal abnormality in fastgrowing poultry birds. It has been considered an economically important disease in poultry that affects poultry industry by carcass loss at meat processing plant due to decrease in disease resistance, production performance, and carcass quality and induces breast cysts and osteomyelitis worldwide. Oxidative stress is developed due to the imbalance of free radical oxygen, which disrupts the equilibrium state of oxidant and antioxidant tending to oxidation. This review is based on the current research, mainly to explore the relationship and mechanism between tibial dyschondroplasia and oxidative stress induced by thiram, which provides a new theoretical foundation for the further research of the related mechanism.
