Catheter angiography and angioplasty in patients with scleroderma
Catheter angiography and angioplasty in patients with scleroderma
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DOI：
10.1259/bjr.74.888.741091
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发表时间：
2001-12-01
影响因子：
2.6
通讯作者：
Watkinson, A
中科院分区：
文献类型：
--
作者：
Dick, EA;Aviv, R;Watkinson, A
这项研究的目的是(I)确定有和没有其他血管危险因素的硬皮病患者的血管造影疾病类型，以及(Ii)确定硬皮病患者中血管造影术和血管成形术有用的患者。本文回顾了8年来26例硬皮病患者接受血管造影和血管成形术的临床资料。血管造影疾病类型使用改良的Brewster分类进行评估。上肢血管造影术显示86%的患者仅有远端疾病，有或没有其他血管危险因素，如吸烟。在下肢中，其他血管危险因素的存在与可能接受血管成形术的大血管疾病之间存在高度显著的相关性，反之，在缺乏其他血管危险因素与下肢远端疾病之间存在高度显著的相关性。在接受血管成形术的5名患者中，有3名患者早期临床效果良好，但远期临床效果较差。上肢血管造影术可能仅能显示远端疾病，而只有当存在其他血管危险因素时，下肢血管造影术和血管成形术才可能有用。
The objectives of this study were (i) to identify patterns of angiographic disease in scleroderma patients with and without other vascular risk factors and (ii) to define patients with scleroderma in whom angiography and angioplasty is useful. The records of 26 patients with scleroderma who underwent angiography and angioplasty over an 8-year period were reviewed. Angiographic disease patterns were assessed using a modified Brewster classification. Angiography of the upper limb demonstrated distal disease alone in 86% of patients, both with and without other vascular risk factors such as smoking. In the lower limb there was a highly significant association between the presence of other vascular risk factors and macrovascular disease potentially amenable to angioplasty, and conversely between the absence of other vascular risk factors and distal disease in the lower limb. Good early but poor late clinical results were achieved in three of five patients who underwent angioplasty. Angiography of the upper limb is likely to demonstrate distal disease alone, and angiography and angioplasty of the lower limb may be useful only if other vascular risk factors are present.