Lung Cancer in China Challenges and Interventions
Lung Cancer in China Challenges and Interventions
复制标题
中国肺癌的挑战和干预措施
DOI：
10.1378/chest.11-2948
复制
发表时间：
2013-04-01
期刊：
影响因子：
9.6
通讯作者：
Bai, Chunxue
中科院分区：
文献类型：
--
作者：
She, Jun;Yang, Ping;Bai, Chunxue
2008年，肺癌取代肝癌成为中国恶性肿瘤患者的头号死因。近30年来，肺癌死亡率上升了464.84%，给患者、医护人员和社会带来了巨大的负担。我们对1990年至2011年中国肺癌的已发表数据进行了系统回顾，以分析癌症的发病率和死亡率、经济负担、危险因素以及干预措施的有效性。中国肺癌发病率各不相同。中国东部的人，尤其是女性，患肺癌的风险可能比中国西部的人更高。2008年，肺癌的粗死亡率为每100 000名男性47.51人，每100 000名女性22.69人。粗死亡率最高的是上海（男性76.49/10万，女性35.82/10万），最低的是西藏（男性25.14/10万）和宁夏（女性12.09/10万）。吸烟和环境污染是中国肺癌的主要危险因素。应继续努力集中对公众进行肺癌教育，以加强预防和早期发现。需要实施具体的干预措施，以降低吸烟率和环境风险因素。中国应采用标准化的治疗方案。胸部2013; 143（4）：1117-1126
In 2008, lung cancer replaced liver cancer as the number one cause of death among people with malignant tumors in China. The registered lung cancer mortality rate increased by 464.84% in the past 3 decades, which imposes an enormous burden on patients, health-care professionals, and society. We performed a systematic review of the published data on lung cancer in China between 1990 and 2011 to analyze the incidence and mortality rates, economic burden, and risk factors of cancer and the effectiveness of interventions. Lung cancer incidence varies within China. People in eastern China, especially women, likely have a higher risk of developing lung cancer than those in western China. The crude mortality rates from lung cancer in 2008 were 47.51 per 100,000 men and 22.69 per 100,000 women. The crude mortality rate was highest in Shanghai (76.49 per 100,000 men and 35.82 per 100,000 women) and lowest in Tibet (25.14 per 100,000 men) and Ningxia (12.09 per 100,000 women). Smoking and environmental pollution are major risk factors for lung cancer in China. Continuous efforts should be concentrated on education of the general public regarding lung cancer to increase prevention and early detection. Specific interventions need to be implemented to reduce smoking rates and environmental risk factors. Standardized treatment protocols should be adapted in China. CHEST 2013; 143(4):1117-1126