Organic-solvent-free electromembrane extraction based on semi-interpenetrating polymer networks
Organic-solvent-free electromembrane extraction based on semi-interpenetrating polymer networks
复制标题
基于半互穿聚合物网络的无有机溶剂电膜萃取
DOI：
10.1039/d1gc00148e
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发表时间：
2021-02-21
期刊：
影响因子：
9.8
通讯作者：
Shen, Xiantao
中科院分区：
文献类型：
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作者：
Mei, Hang;Liu, Huajing;Shen, Xiantao
本工作提出了一种基于半互穿聚合物网络（semi-IPN）的绿色、稳定、通用的无有机溶剂电膜萃取（EME）体系，用于从人尿中萃取和富集碱性和酸性药物。由于其无毒和高亲和力的目标分离，半固体聚丙二醇（PPG）被选为通过超声辅助共混（UAB）方法合成的半互穿网络网络的一个组成部分。采用均相半互穿网络膜作为支撑液膜，得到了无有机溶剂的电磁萃取体系。在优化条件下，无有机溶剂的EME体系对碱性分析物（70-97%）和酸性分析物（86-100%）均表现出较高的回收率。此外，无有机溶剂的EME设置可以重复使用在8个连续的提取批次，而不会显着降低提取效率。此外，该系统可以方便地在室温下长期储存，这将大大促进EME的商业化。本研究为绿色样品制备方法的发展提供了新的思路和尝试。
In this work, a green, stable and versatile organic-solvent-free electromembrane extraction (EME) system based on semi-interpenetrating polymer networks (semi-IPN) is proposed for the extraction and enrichment of both basic and acidic drugs from human urine. Because of its non-toxicity and high affinity in target separation, semi-solid polypropylene glycol (PPG) was selected as a component for the synthesis of semi-IPN networks via an ultrasonic-assisted blending (UAB) method. Using the homogeneous semi-IPN membrane as the supported liquid membrane (SLM), the organic-solvent-free EME system was obtained. Under the optimized conditions, the organic-solvent-free EME system showed high recovery efficiency for both basic analytes (70-97%) and acidic analytes (86-100%). Moreover, the organic-solvent-free EME set-up could be reused in eight successive extraction batches without an obvious decrease in extraction efficiency. In addition, the EME system could be conveniently stored at ambient temperature for a long time, which will greatly promote the commercialization of EME. We believe this study provides new insights and attempts in the development of green sample preparation approaches.