Design and implementation of an anthropomorphic quality assurance phantom for intensity-modulated radiation therapy for the radiation therapy oncology group
Design and implementation of an anthropomorphic quality assurance phantom for intensity-modulated radiation therapy for the radiation therapy oncology group
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DOI：
10.1016/j.ijrobp.2005.05.021
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发表时间：
2005-10-01
影响因子：
7
通讯作者：
Ibbott, GS
中科院分区：
文献类型：
--
作者：
Molineu, A;Followill, DS;Ibbott, GS
目的：设计、构建和评估一个拟人化模型，用于评估调强放射治疗（IMRT）剂量计划和递送，用于放射治疗肿瘤小组（RTOG）和其他合作小组制定的方案。方法和材料：用塑料头状外壳和水当量塑料制成假体。内部结构模拟计划目标体积和处于危险中的器官。用热释光剂量计（TLDs）和放射致色膜分别测量了绝对剂量和剂量分布。在IMRT治疗中验证了幻影剂量计的可重复性，然后由10个RTOG机构对幻影进行成像，计划和照射。结果：三次相同辐照的TLD结果的标准偏差小于1.6%，膜扫描系统重现性在0.35 mm以内。从10个机构收集的辐照数据显示，TLD与机构的剂量一致，在规划目标体积的+/- 5%标准偏差范围内，在危险器官的标准偏差范围内为+/- 13%。用薄膜检测到治疗计划和递送之间最大8毫米的位移。结论：利用TLD和放射显色膜的拟人化幻影可以验证IMRT治疗的剂量传递和野场放置。(c) 2005爱思唯尔公司
Purpose: To design, construct, and evaluate an anthropomorphic phantom for evaluation of intensity-modulated radiation therapy (IMRT) dose planning and delivery, for protocols developed by the Radiation Therapy Oncology Group (RTOG) and other cooperative groups.Methods and Materials: The phantom was constructed from a plastic head-shaped shell and water-equivalent plastics. Internal structures mimic planning target volumes and an organ at risk. Thermoluminescent dosimeters (TLDs) and radiochromic film were used to measure the absolute dose and the dose distribution, respectively. The reproducibility of the phantom's dosimeters was verified for IMRT treatments, and the phantom was then imaged, planned, and irradiated by 10 RTOG institutions.Results: The TLD results from three identical irradiations showed a percent standard deviation of less than 1.6%, and the film-scanning system was reproducible to within 0.35 mm. Data collected from irradiations at 10 institutions showed that the TLD agreed with institutions' doses to within +/- 5% standard deviation in the planning target volumes and +/- 13% standard deviation in the organ at risk. Shifts as large as 8 mm between the treatment plan and delivery were detected with the film.Conclusions: An anthropomorphic phantom using TLD and radiochromic film can verify dose delivery and field placement for IMRT treatments. (c) 2005 Elsevier Inc.