Right Ventricular Imaging in 25 Seconds: Evaluating the Use of Sparse Sampling CINE With Iterative Reconstruction for Volumetric Analysis of the Right Ventricle
Right Ventricular Imaging in 25 Seconds: Evaluating the Use of Sparse Sampling CINE With Iterative Reconstruction for Volumetric Analysis of the Right Ventricle
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DOI：
10.1097/rli.0000000000000250
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发表时间：
2016-06-01
影响因子：
6.7
通讯作者：
Papavassiliu, Theano
中科院分区：
文献类型：
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作者：
Haubenreisser, Holger;Henzler, Thomas;Papavassiliu, Theano
目的本研究的目的是前瞻性地评价使用稀疏数据采样迭代重建（SSIR）的二维实时CINE TrueFISP磁共振序列用于右心室（RV）容量测定，并与在3 t时获得的标准标准（CS）进行比较。材料和方法10名健康对照者和20名连续患者计划在3- t系统(Magnetom Skyra；西门子医疗保健部门，德国)进行了单次屏气（BH）和浅自由呼吸（NBH）的欠采样SSIR序列，以及完全采样的多BH序列作为CS。右心室容量测量采用专用心脏磁共振软件（cvi42; Circle Cardiovascular Imaging Inc, Calgary, Alberta, Canada）。采用Bland-Altman分析和配对t检验，评估SSIR在有和没有BH和CS的情况下，对RV功能参数（收缩末容积[RVESV]、舒张末容积[RVEDV]、卒中容积[RVSV]和射血分数[RVEF]）的一致性。结果30例患者（男性19例，14岁48例）的CS和BH检测RVEDV （153.7 vs 153.6 mL, P = 0.96）、RVESV （71.6 vs 72.1 mL, P = 0.78）、RVSV （82.0 vs 81.6 mL, P = 0.65）和RVEF （54.9% vs 54.2%, P = 0.19）的差异无统计学意义。当比较CS和NBH测量RVEDV （153.7 vs 152.2 mL, P = 0.34）、RVESV （71.6 vs 72.8 mL, P = 0.30）、RVSV （82.0 vs 81.0 mL, P = 0.46）和RVEF （54.9 vs 54.4, P = 0.48）时，也显示了类似的结果。采集时间CS为350秒，BH为34秒，NBH为25秒。对于稀疏采样数据集，迭代重建所需的额外时间为2分30秒。结论：我们的研究结果表明，在临床常规中，即使没有BH，在3t时使用SSIR数据进行准确的右心室容量测量也是可行的，这对呼吸困难患者尤为重要。
Objective The aim of this study was to prospectively evaluate a 2-dimensional real-time CINE TrueFISP magnetic resonance sequence using sparse data sampling with iterative reconstruction (SSIR) for right ventricular (RV) volumetry in comparison to the criterion standard (CS) acquired at 3 T.Materials and Methods Ten healthy controls and 20 consecutive patients scheduled for cardiac magnetic resonance imaging on a 3-T system (Magnetom Skyra; Siemens Healthcare Sector, Germany) underwent undersampled SSIR sequences with a single breath-hold (BH) as well as with shallow free breathing (NBH) and a fully sampled multi-BH sequence as CS. Right ventricular volumetry was performed with dedicated cardiac magnetic resonance software (cvi42; Circle Cardiovascular Imaging Inc, Calgary, Alberta, Canada). Agreement of SSIR with and without BH and CS for RV functional parameters (end-systolic volume [RVESV], end-diastolic volume [RVEDV], stroke volume [RVSV], and ejection fraction [RVEF]) were assessed with Bland-Altman analysis and paired t test.Results Analysis of the 30 individuals (19 male; 48 14 years) revealed no significant differences when comparing CS and BH measurements for RVEDV (153.7 vs 153.6 mL, P = 0.96), RVESV (71.6 vs 72.1 mL, P = 0.78), RVSV (82.0 vs 81.6 mL, P = 0.65), and RVEF (54.9% vs 54.2%, P = 0.19). Similar results were shown when comparing CS and NBH measurements for RVEDV (153.7 vs 152.2 mL, P = 0.34), RVESV (71.6 vs 72.8 mL, P = 0.30), RVSV (82.0 vs 81.0 mL, P = 0.46), and RVEF (54.9 vs 54.4, P = 0.48). Time taken for acquisition was 350 seconds for the CS, 34 seconds for BH, and 25 seconds for NBH measurements. Additional time required for iterative reconstruction was 2 minutes and 30 seconds for the sparse sampled data sets.Conclusions Our results demonstrate that accurate RV volumetry with SSIR data at 3 T is feasible in clinical routine within 25 seconds even without BH, which is of particular importance in patients with dyspnea.