Optimization of microfluidic particle sorters based on dielectrophoresis
Optimization of microfluidic particle sorters based on dielectrophoresis
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DOI：
10.1109/jsen.2005.844333
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发表时间：
2005-09
影响因子：
4.3
通讯作者：
J. H. Nieuwenhuis;A. Jachimowicz;P. Svasek;M. Vellekoop
中科院分区：
文献类型：
--
作者：
J. H. Nieuwenhuis;A. Jachimowicz;P. Svasek;M. Vellekoop
本文介绍了改进的介电泳颗粒分选机在微流体中的应用。简要讨论了电极的最佳形状，并介绍了两种新的分选器拓扑。基于理论考虑，详细分析了四种分拣机配置。这些设备是通过有限元模拟和分析计算相结合计算粒子轨迹来建模的。四种分类器配置已在基于硅、玻璃和 SU8 技术的芯片中实现。模拟和实验结果非常一致，并证实采用新的分选机配置，与文献中发现的经典线电极相比，可以实现更高的性能 (+200%)。
In this paper, improved dielectrophoretic particle sorters are introduced for application in microfluidics. The optimal shape of the electrodes is briefly discussed and two new sorter topologies are introduced. Based on the theoretical considerations, four sorter configurations are analyzed in detail. The devices are modeled by calculating the particle trajectories from a combination of finite-element simulations and analytical calculations. The four sorter configurations have been realized in chips based on silicon, glass, and SU8 technology. The simulations and the experimental results are in very good agreement and confirm that with the new sorter configurations, much higher performance can be realized (+200%) compared to the classical line electrodes found in literature.