Chemically Modifying Viruses for Diverse Applications.
Chemically Modifying Viruses for Diverse Applications.
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DOI:
10.1021/acschembio.6b00060
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发表时间:
2016-05-20
影响因子:
4
通讯作者:
Weiss GA
中科院分区:
文献类型:
--
作者:
Mohan K;Weiss GA
Long fascinating to biologists, viruses offer nanometer-scale benchtops for building molecular-scale devices and materials. Viruses tolerate a wide-range of chemical modifications including reaction conditions, pH values, and temperatures. Recent examples of non-genetic manipulation of viral surfaces have extended viruses into applications ranging from biomedical imaging, drug delivery, tissue regeneration, and biosensors to materials for catalysis and energy generation. Chemical reactions on the phage surface include both covalent and non-covalent modifications, including some applied in conjunction with genetic modifications. Here, we survey viruses chemically augmented with capabilities limited only by imagination.
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