Ophthalmic fundus imaging: Today and beyond

Ophthalmic fundus imaging: Today and beyond
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DOI:
10.1016/j.ajo.2003.12.035
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发表时间:
2004-03-01
影响因子:
4.2
通讯作者:
Rosen, R
Rosen, R
中科院分区:
医学1区
文献类型:
--
作者:
Yannuzzi, LA;Ober, MD;Rosen, R

文献摘要

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目得:回顾和更新眼后段眼底成像技术。设计:文献综述和作者的集体经验。方法:这一观点包括数字成像、眼底自发荧光、超声、血管造影和光学相干断层扫描(OCT)-检眼镜等部分,由这些领域的主要临床医生和研究人员撰写。结果:数字血管造影术已成为眼科界的新标准,其基于改进的技术,该技术具有增强的分辨率、处理时间以及图像复制、操作和传输的简易性。一种相对较新的成像技术,眼底自发荧光,突出脂褐素沉积,提高了我们对视网膜色素上皮细胞代谢状态的理解。超声诊断仍然是眼部评估的主要辅助手段,现在的进步允许特殊的多功能性和便携性。高速血管造影技术提供了脉络膜灌注的详细可视化,提高了我们对正常和病理血管现象的理解。目前正在开发的高分辨率OCT的进步承诺了更详细的眼底表示。扫描激光检眼镜和OCT的集成产生了一种动态的新仪器,OCT检眼镜,它同时以多种方式与点对点correlations.CONCLUSIONS:眼科成像技术彻底改变了眼底检查。目前可用的系统对我们理解各种视网膜疾病的病理生理学和治疗做出了重大贡献。未来的进展承诺近组织学分辨率的视网膜结构,以及真实的,时间图像处理和瞬时传输的世界,广泛。(C)2004年,Elsevier Inc. All rights reserved.
PURPOSE: To review and update techniques of posterior segment ophthalmic fundus imaging.DESIGN: Literature review and collective experience of the authors.METHODS: This perspective includes sections on digital imaging, fundus autofluorescence, ultrasonography, angiography, and optical coherence tomography (OCT)-ophthalmoscopy written by leading clinicians and researchers in these areas.RESULTS: Digital angiography has become the new standard in the ophthalmic community based upon im proved technology which has enhanced resolution, processing time, and ease of image duplication, manipulation, and transmission. A relatively new imaging technique, fundus autofluorescence, highlights lipofuscin deposits and improves our understanding of the metabolic status of the retinal pigment epithelium. Diagnostic ultrasonography continues to be a major adjunct to ocular evaluation where advances now allow for exceptional versatility and portability. High speed angiographic techniques provide detailed visualization of choroidal perfusion which improves our understanding of both normal and pathologic vascular phenomenon. Advances in high-resolution OCT currently under development promise an even more detailed fundus representation. The integration of the scanning laser ophthalmoscope and OCT has produced a dynamic new instrument, the OCT ophthalmoscope, which simultaneously images the fundus in numerous ways with point to point correlation.CONCLUSIONS: Ophthalmic imaging technology has revolutionized fundus examination. Currently available systems have contributed significantly to our understanding of the pathophysiology and treatment of various retinal diseases. Future advances promise near histologic resolution of retinal structures as well as real,time image manipulation and instantaneous transmission world, wide. (C) 2004 by Elsevier Inc. All rights reserved.