Vacuum-assisted closure therapy and wound coverage in soft tissue injury
Vacuum-assisted closure therapy and wound coverage in soft tissue injury
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DOI：
10.1007/s00113-007-1265-z
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发表时间：
2007-04-01
期刊：
影响因子：
--
通讯作者：
Pelzer, M.
中科院分区：
文献类型：
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作者：
Holle, G.;Germann, G.;Pelzer, M.
本研究介绍了一项荟萃分析的结果，该分析基于涉及真空辅助闭合（VAC）在慢性伤口、急性创伤后伤口、筋膜室综合征或上肢损伤领域的临床应用的文献。分析了这些研究的有效性、成功率、出版物和经济效益方面结论的意义，数据表明VAC是一种非常有价值的技术，已被添加到软组织重建的综合治疗概念中。然而，来自前瞻性随机试验的临床数据仍然缺失，以支持该技术在日常临床应用中看到的一些积极方面。这将为证明该技术的经济效益奠定坚实的基础。
This study presents the results of a meta-analysis based on the literature dealing with the clinical applications of vacuum-assisted closure (VAC) in the areas of chronic wounds, acute posttraumatic wounds, compartment syndromes, or injuries of the upper extremities. The studies were analysed for validity, significance of conclusion with respect to success rate, publications, and economic efficacy.The data show that with VAC a very valuable technique has been added to an integrated therapeutic concept of soft tissue reconstruction. However, clinical data from prospective randomised trials to support some of the positive aspects seen in the daily clinical application of the technique are still missing. These would create a sound basis demonstrating the economic efficacy of the technique.