Formal synthesis of (±)-guanacastepene A:: A tandem ring-closing metathesis approach

Formal synthesis of (±)-guanacastepene A:: A tandem ring-closing metathesis approach
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DOI:
10.1021/ol049452x
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发表时间:
2004-05-27
期刊:
影响因子:
5.2
通讯作者:
Ricard, L
Ricard, L
中科院分区:
化学1区
文献类型:
--
作者:
Boyer, FD;Hanna, I;Ricard, L

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A concise route to a key intermediate in the total synthesis of guanacastepene A is described. The main features include the simultaneous construction of the seven- and six-membered rings, using a tandem ring-closing metathesis and a stereoselective introduction of the oxygenated function at the C5 position.