Response selection in the human anterior cingulate cortex
Response selection in the human anterior cingulate cortex
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DOI：
10.1038/13224
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发表时间：
1999-10-01
影响因子：
25
通讯作者：
Swick, D
中科院分区：
文献类型：
--
作者：
Turken, AU;Swick, D
前扣带皮层 (ACC) 被认为是大脑注意力控制网络的一部分，但其参与认知和运动操作的确切性质仍存在争议。评估人体 ACC 损伤的影响直接解决 ACC 功能问题。我们报告称，患有局灶性右半球前扣带回病变的患者的执行控制过程并未受到损害。然而，她的表现水平取决于所使用的反应方式。在相同的任务要求下，她在进行手动响应时受到了损害，但在进行声音响应时却没有受到损害。因此，我们为人类 ACC 内的功能专业化提供了神经心理学证据。
The anterior cingulate cortex (ACC) has been proposed as part of the brain's attentional control network, but the exact nature of its involvement in cognitive and motor operations is under debate. Assessing effects of human ACC damage directly addresses the problem of ACC function. We report that executive control processes of a patient with a focal right hemisphere anterior cingulate lesion were not compromised. However, her performance level depended on the response modality used. Under the same task requirements, she was impaired when giving manual responses, but not vocal responses. Thus, we provide neuropsychological evidence for functional specialization within the human ACC.