Optical deformability of soft biological dielectrics
Optical deformability of soft biological dielectrics
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DOI：
10.1103/physrevlett.84.5451
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发表时间：
2000-06-05
影响因子：
8.6
通讯作者：
Käs, J
中科院分区：
文献类型：
--
作者：
Guck, J;Ananthakrishnan, R;Käs, J
利用两束反向传播的激光束对细胞等软组织进行了拉伸实验。变形力作用在物体与周围介质之间的表面上，且远高于物体上的捕获力。避免了辐射损伤，因为双光束阱不需要聚焦来稳定捕获。用射线光学描述了被困物体表面的应力分布。测量定义明确的弹性物体的总力和变形验证了这种方法。
Two counterpropagating laser beams were used to significantly stretch soft dielectrics such as cells, The deforming forces act on the surface between the object and the surrounding medium and are considerably higher than the trapping forces on the object. Radiation damage is avoided since a double-beam trap does not require focusing for stable trapping. Ray optics was used to describe the stress profile on the surface of the trapped object. Measuring the total forces and deformations of well-defined elastic objects validated this approach.