CLINICAL COURSE OF PERTUSSIS IN IMMUNIZED CHILDREN

CLINICAL COURSE OF PERTUSSIS IN IMMUNIZED CHILDREN
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DOI:
10.1097/00006454-199510000-00010
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发表时间:
1995-10-01
影响因子:
3.6
通讯作者:
HALPERIN, S
HALPERIN, S
中科院分区:
医学4区
文献类型:
--
作者:
BORTOLUSSI, R;MILLER, B;HALPERIN, S

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为了描述高度免疫儿童人群中百日咳杆菌感染的临床过程,我们前瞻性研究了1987年至1994年8年间免疫率>90%的大城市人群中的地方性和流行性百日咳。可能诊断为百日咳的患者由家庭医生或急诊室医生转诊进行鼻咽培养,B培养阳性的患者。由一名护士联系百日咳患者,该护士完成了对索引病例和所有家庭成员的详细问卷调查,每周进行重复家访,持续4周。
To describe the clinical course of Bordetella pertussis infection in a highly immunized childhood population, we studied prospectively endemic and epidemic pertussis in a metropolitan population with an immunization rate >90% during an 8-year period from 1987 through 1994. Patients with a possible diagnosis of pertussis were referred by family or emergency room physicians for nasopharyngeal culture, Patients with a culture positive for B. pertussis were contacted by a nurse who completed a detailed questionnaire for the index case and all family members, Repeat home visits were made each week for 4 weeks, Of the 189 patients with pertussis who were evaluated 103 subjects were