Evaluation of available IgE-binding epitope data and its utility in bioinformatics
Evaluation of available IgE-binding epitope data and its utility in bioinformatics
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DOI：
10.1002/mnfr.200500276
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发表时间：
2006-07-01
影响因子：
5.2
通讯作者：
Ogawa, Tadashi
中科院分区：
文献类型：
--
作者：
Bannon, Gary A.;Ogawa, Tadashi
本文综述了IgE结合表位在引起临床症状中的作用、变应原蛋白中IgE结合表位的类型、识别IgE结合表位的方法以及变应原来源中IgE结合表位的可用性。最后，生物信息学方法来评估蛋白质过敏性IgE结合表位的知识进行了讨论。
This paper reviews the role played by IgE-binding epitopes in eliciting clinical symptoms, the types of IgE-binding epitopes in allergenic proteins, the methods used to identify IgE-binding epitopes, and the availability of IgE-binding epitopes in allergenic sources. Finally, bioinformatics methods to assess protein allergenicity using knowledge of IgE-binding epitopes are discussed.