Cardiac fluid dynamics.
Cardiac fluid dynamics.
复制标题
DOI：
10.1201/9781003068136-4
复制
发表时间：
1992
影响因子：
--
通讯作者：
C. Peskin;D. McQueen
中科院分区：
文献类型：
--
作者：
C. Peskin;D. McQueen
心脏被建模为一个系统的弹性和/或收缩性纤维浸没在粘性不可压缩流体。通过根据心脏壁中的肌肉纤维和瓣膜小叶中的胶原纤维的实际分布的理想化版本排列纤维来构造模拟的心脏壁和瓣膜。通过对流体-纤维系统耦合运动方程的数值求解，预测了流体-纤维系统的联合运动。流体方程求解有限差分法在一个固定的，定期的计算网格。纤维点在晶格中自由移动，而不会被约束为位于晶格交点处。纤维和流体之间的通信涉及流体速度到纤维点的插值和纤维力到流体的计算网格的扩展。这两种操作都利用了狄拉克δ函数的平滑近似。整个方法适用于向量、并行或并行向量硬件上的实现。应用包括正常心脏功能的研究，影响心脏或其瓣膜机械功能的疾病过程的模拟，以及人工心脏瓣膜的计算机辅助设计。
The heart is modeled as a system of elastic and/or contractile fibers immersed in a viscous incompressible fluid. Simulated heart walls and valves are constructed by arranging the fibers according to an idealized version of the actual distribution of muscle fibers in the heart walls and collagen fibers in the valve leaflets. Then the combined motion of the fluid-fiber system is predicted through the numerical solution of its coupled equations of motion. Fluid equations are solved by a finite difference method on a fixed, regular computational lattice. Fiber points move freely through this lattice without being constrained to lie at the lattice intersections. Communication between fibers and fluid involves interpolation of the fluid velocity to the fiber points and the spreading of the fiber forces to the computational lattice of the fluid. Both of these operations make use of a smoothed approximation to the Dirac delta function. The entire method is suitable for implementation on vector, parallel, or parallel-vector hardware. Applications include the investigation of normal cardiac function, the simulation of disease processes affecting the mechanical function of the heart or its valves, and the computer-assisted design of prosthetic cardiac valves.