Gender differences in daily ambulatory activity patterns in patients with intermittent claudication
Gender differences in daily ambulatory activity patterns in patients with intermittent claudication
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DOI：
10.1016/j.jvs.2010.05.115
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发表时间：
2010-11-01
影响因子：
4.3
通讯作者：
Blevins, Steve M.
中科院分区：
文献类型：
--
作者：
Gardner, Andrew W.;Parker, Donald E.;Blevins, Steve M.
目的：比较间歇性跛行男性和女性患者的日常步行活动模式，并确定小腿肌血红蛋白氧饱和度（StO（2））是否与日常步行活动相关。方法：40名男性和41名女性患有局限于间歇性跛行的外周动脉疾病，对他们基于社区的步行活动模式进行了为期1周的评估，结果：女性的调整后每日最大踏频低于男性，女性的调整后每日最大踏频高于女性（平均值+/- SE）持续5分钟的Ambassador（26.2 +/- 1.2步/分vs 31.0 +/- 1.2步/分; P = 0.009），1分钟的步行（43.1 +/- 0.9步/分vs 47.2 +/- 0.9步/分; P = .004），间歇性步行由峰值活动指数确定（26.3 +/- 1.2步/分vs 31.0 +/- 1.2步/分; P = 0.009）。女性在运动过程中达到最小小腿肌肉StO（2）的调整时间也较短（P = 0.048），这与连续5分钟的最大踏频（r = 0.51; P <0.01）、1分钟的最大踏频（r = 0.42; P <0.05）和峰值活动指数（r = 0.44; P <0.05）呈正相关。这些协会没有显着的男性。结论：间歇性跛行的妇女在社区环境中比男性走动慢，特别是短的连续时间长达5分钟，间歇性跛行期间在高峰节奏。此外，女性的每日步行节奏与运动期间的小腿肌肉StO（2）相关，因为在社区环境中走路较慢的女性比那些以较快速度走路的女性更快地达到小腿肌肉StO（2）的最小值。应鼓励间歇性跛行的女性不仅要每天多走路，而且要以比他们喜欢的速度快的速度走路。（J Vase Surg 2010;52：1204-10.）
Objectives: To compare the pattern of daily ambulatory activity in men and women with intermittent claudication, and to determine whether calf muscle hemoglobin oxygen saturation (StO(2)) is associated with daily ambulatory activity.Methods: Forty men and 41 women with peripheral arterial disease limited by intermittent claudication were assessed on their community-based ambulatory activity patterns for 1 week with an ankle-mounted step activity monitor and on calf muscle StO(2) during a treadmill test.Results: Women had lower adjusted daily maximal cadence (mean +/- SE) for 5 continuous minutes of ambulation (26.2 +/- 1.2 strides/min vs 31.0 +/- 1.2 strides/min; P = .009), for 1 minute of ambulation (43.1 +/- 0.9 strides/min vs 47.2 +/- 0.9 strides/min; P = .004), and for intermittent ambulation determined by the peak activity index (26.3 +/- 1.2 strides/min vs 31.0 +/- 1.2 strides/min; P = .009). Women also had lower adjusted time to minimum calf muscle StO(2) during exercise (P = .048), which was positively associated with maximal cadence for 5 continuous minutes (r = 0.51; P < .01), maximal cadence for 1 minute (r = 0.42; P < .05), and peak activity index (r = 0.44; P < .05). These associations were not significant in men.Conclusion: Women with intermittent claudication ambulate slower in the community setting than men, particularly for short continuous durations of up to 5 minutes and during intermittent ambulation at peak cadences. Furthermore, the daily ambulatory cadences of women are correlated with their calf muscle StO(2) during exercise, as women who walk slower in the community setting reach their minimum calf muscle StO(2) sooner than those who walk at faster paces. Women with intermittent claudication should be encouraged to not only walk more on a daily basis, but to do so at a pace that is faster than their preferred speed. (J Vase Surg 2010;52:1204-10.)