DIETARY RESTRICTION IN MICE BEGINNING AT 1 YEAR OF AGE - EFFECT ON LIFE-SPAN AND SPONTANEOUS CANCER INCIDENCE
DIETARY RESTRICTION IN MICE BEGINNING AT 1 YEAR OF AGE - EFFECT ON LIFE-SPAN AND SPONTANEOUS CANCER INCIDENCE
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DOI：
10.1126/science.7063854
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
WALFORD, RL
中科院分区：
文献类型：
--
作者：
WEINDRUCH, R;WALFORD, RL
食物的摄入量为12- 13个月。按照营养不足而非营养不良的概念，对2个长寿品系的10岁小鼠进行营养强化饮食限制。与对照组小鼠相比，限制饮食组小鼠的平均和最长生存时间平均增加了10-20%。自发性淋巴瘤受到食物限制的抑制。
The food intake of 12- to 13-mo.-old mice of 2 long-lived strains was restricted by using nutrient-enriched diets in accordance with the concept of undernutrition without malnutrition. The mice on the restricted diet averaged 10-20% increases in mean and maximum survival times compared to the control mice. Spontaneous lymphoma was inhibited by the food restriction.