Phaco-trabectome versus phaco-iStent in patients with open-angle glaucoma
Phaco-trabectome versus phaco-iStent in patients with open-angle glaucoma
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DOI：
10.1016/j.jcjo.2016.06.018
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发表时间：
2017-02-01
影响因子：
4.2
通讯作者：
Dorey, Michael W.
中科院分区：
文献类型：
--
作者：
Kurji, Khaliq;Rudnisky, Christopher J.;Dorey, Michael W.
目的：研究超声乳化小梁切除术（PT）与超声乳化iStent（Pi）控制开角型青光眼（OAG）眼内压（IOP）的有效性和安全性。设计：回顾性比较病例系列。参与者：55例OAG患者共70只眼，由单一外科医生进行PT手术或Pi手术。2010年1月至2012年12月期间，另一名外科医生在加拿大植入了2枚支架。方法：回顾了接受PT或Pi手术的连续成人患者的病历。所有符合入选和排除标准的患者均纳入结局分析。眼压降低，减少青光眼药物，安全性，最佳矫正视力evaluated.Results：36眼的30例患者PT和34眼的25例患者Pi。PT组的基线IOP（20.92 +/- 5.07 mm Hg）高于Pi组（17.47 +/- 4.87 mm Hg; p = 0.026）。在12个月时，两组平均IOP的相对降低无显著差异（PT - 5.09 +/- 5.73，相对降低24% vs. Pi - 3.84 +/- 3.80，相对降低22%; p = 0.331）或使用青光眼药物（PT - 0.49 +/- 1.17 vs. Pi - 0.26 +/- 0.73; p = 0.168）。然而，Pi在整个术后期间的个体并发症显著较少（PT 20 vs. Pi 5; p < 0.0001）。结论：在12个月的随访中，两种技术均显著降低了IOP，但Pi组的并发症较少。(C)2017年加拿大眼科学会。爱思唯尔公司出版
Objective: To investigate efficacy and safety of phaco-trabectome(PT) versus phaco-iStent(Pi) for intraocular pressure(IOP) control in open-angle glaucoma (OAG).Design: Retrospective comparative case series.Participants: A total of 70 eyes of 55 patients with OAG underwent either PT surgery by a single surgeon or Pi (insertion of 2 stents) by another surgeon in Canada between January 2010 and December 2012.Methods: The medical records of consecutive adult patients who underwent either PT or Pi surgery were reviewed. All patients who satisfied both the inclusion and exclusion criteria were included in the outcomes analyses. IOP reduction, reduction in glaucoma medication, safety profile, and best-corrected visual acuity were evaluated.Results: Thirty-six eyes of 30 patients had PT and 34 eyes of 25 patients had Pi. Baseline IOP was higher in the PT group (20.92 +/- 5.07 mm Hg) than in the Pi group(17.47 +/- 4.87 mm Hg; p = 0.026). At 12 months there was no significant difference between groups in relative reduction of mean IOP (PT - 5.09 +/- 5.73, 24% relative reduction vs. Pi - 3.84 +/- 3.80, 22% relative reduction; p = 0.331) or glaucoma medication use (PT - 0.49 +/- 1.17 vs. Pi - 0.26 +/- 0.73; p = 0.168) from baseline. However, Pi had significantly fewer individual complications (PT 20 vs. Pi 5; p < 0.0001) throughout the postoperative period.Conclusion: At 12 months of follow-up, both techniques significantly lowered IOP, but fewer complications were observed in the Pi group. (C) 2017 Canadian Ophthalmological Society. Published by Elsevier Inc.