Behavioral responses to noxious stimuli shape the perception of pain.
Behavioral responses to noxious stimuli shape the perception of pain.
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DOI：
10.1038/srep44083
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发表时间：
2017-03-09
影响因子：
4.6
通讯作者：
Ploner M
中科院分区：
文献类型：
--
作者：
May ES;Tiemann L;Schmidt P;Nickel MM;Wiedemann N;Dresel C;Sorg C;Ploner M
疼痛具有重要的保护功能。为了实现这些功能，有害刺激可能会引发一种感知，进而引发行为反应。在这里，我们研究了另一种观点，即行为反应并不完全依赖于行为反应，而是行为反应本身塑造了感知。我们在一项实验中测试了这一假设，其中健康人类受试者执行反应时间任务并提供有害和触觉刺激的感知评级。多层次调节中介分析表明，行为反应在刺激转化为感知的过程中发挥着重要作用。这种参与对有害刺激的影响明显强于对触觉刺激的参与。这些发现表明，行为反应对感知的影响对于疼痛尤其强烈，这可能反映了行为反应与保护身体的最大相关性。这些观察结果与最近的情绪概念相似，并对疼痛的理解和治疗产生了影响。
Pain serves vital protective functions. To fulfill these functions, a noxious stimulus might induce a percept which, in turn, induces a behavioral response. Here, we investigated an alternative view in which behavioral responses do not exclusively depend on but themselves shape perception. We tested this hypothesis in an experiment in which healthy human subjects performed a reaction time task and provided perceptual ratings of noxious and tactile stimuli. A multi-level moderated mediation analysis revealed that behavioral responses are significantly involved in the translation of a stimulus into perception. This involvement was significantly stronger for noxious than for tactile stimuli. These findings show that the influence of behavioral responses on perception is particularly strong for pain which likely reflects the utmost relevance of behavioral responses to protect the body. These observations parallel recent concepts of emotions and entail implications for the understanding and treatment of pain.