The 14-year course of alcoholism in a community sample: Do men and women differ?
The 14-year course of alcoholism in a community sample: Do men and women differ?
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DOI：
10.1016/j.drugalcdep.2007.08.013
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发表时间：
2008-01-11
影响因子：
4.2
通讯作者：
Bucholz, Kathleen K.
中科院分区：
文献类型：
--
作者：
Edens, Ellen L.;Glowinski, Anne L.;Bucholz, Kathleen K.
目的：通过对 DSM-III 酗酒者与社区样本中的重度饮酒者和未受影响的对照者进行 14 年随访，调查男性和女性的酗酒病程。 方法：基于 1997 年卫生服务使用和成本研究数据的病例对照研究，该研究对参加 1981-1983 年圣路易斯流行病学两波调查的 442 人进行了 14 年跟踪调查集水区研究。两波 ECA 中的病例均符合 DSM-III 酒精滥用 (AA) 或酒精依赖 (AD) 标准：“两次酒精使用障碍阳性 (ECA 2t-AUDP)”。两个比较组的频率调整为 2t-AUDP：(1) ECA 重度饮酒者/一次性酒精使用障碍阳性 (ECA VHD/1t-AUDP) 和 (2) ECA 酒精不受影响。报告了男性和女性的终生和过去一年的酒精使用障碍、饮酒模式和恢复情况。结果：84.6% 的 2t-AUDP 在 14 年随访中再次符合终生 DSM-III 标准。随访时，只有 9.3% 的男性 2t-AUDP 和 20.7% 的女性 2t-AUDP 符合去年 DSM-IV AUD 标准。然而，过去一年的饮酒模式显示，与 ECA VHD/1t-AUDP 人群 (41.2%) 和不受影响的 ECA 人群 (22.1%) 相比，2t-AUDP 人群 (61.7%) 的 DSM-IV AA 或 AD、问题或风险饮酒率较高。结论：在社区样本中，男性 2t-AUDP 人群过去一年的 DSM-IV 酒精依赖率低于女性，尽管两组均较低显示过去一年的利率大大低于终生利率。然而，不到一半的 ECA 2t-AUDP 表现出低风险或戒酒行为，这表明虽然诊断缓解很常见，但临床相关性仍然存在。 (c) 2007 Elsevier Ireland Ltd. 保留所有权利。
Objective: To investigate the course of alcoholism in males and females in a 14-year follow-up of persons with DSM-III alcoholism compared to very heavy drinkers and unaffected controls in a community sample.Methods: Case-control study based on data from the 1997 Health Services Use and Cost study, a 14-year follow-up survey of 442 individuals who participated in two waves of the 1981-1983 St. Louis Epidemiologic Catchment Area study. Cases met criteria for DSM-III alcohol abuse (AA) or dependence (AD) at both waves of the ECA: "Two-times Alcohol Use Disorder Positives (ECA 2t-AUDPs)." Two comparison groups were frequency thatched to 2t-AUDPs: (1) ECA Very Heavy Drinkers/One-time Alcohol Use Disorder Positives (ECA VHD/1t-AUDPs) and (2) ECA alcohol-unaffecteds. Lifetime and past year alcohol use disorders, patterns of drinking and recovery among males and females are reported.Results: 84.6% of 2t-AUDPs again met lifetime DSM-III criteria at 14-year follow-up. At follow-up, only 9.3% male 2t-AUDPs and 20.7% female 2t-AUDPs met past year DSM-IV AUD criteria. Past year drinking patterns, however, revealed higher rates of DSM-IV AA or AD, problem or risk drinking among 2t-AUDPs (61.7%) compared to both ECA VHD/1t-AUDPs (41.2%) and ECA alcohol-unaffecteds (22.1 %).Conclusions: In a community sample, the rate of past year DSM-IV alcohol dependence was lower among male 2t-AUDPs than females, though both groups showed past year rates substantially lower than lifetime rates. However, less than half of ECA 2t-AUDPs exhibited low-risk or abstinent alcohol use behaviors, indicating that while remission from diagnosis is common, clinical relevance persists. (c) 2007 Elsevier Ireland Ltd. All rights reserved.