Adaptation to contingencies in macaque primary visual cortex
Adaptation to contingencies in macaque primary visual cortex
复制标题
DOI：
10.1098/rstb.1997.0098
复制
发表时间：
1997-08-29
影响因子：
6.3
通讯作者：
Movshon, JA
中科院分区：
文献类型：
--
作者：
Carandini, M;Barlow, HB;Movshon, JA
我们测试了初级视觉皮质(VI)的神经元选择性地适应视觉刺激属性的偶然性的假设。我们记录了猕猴VI的单个神经元，并测量了对两个栅格的总和(复合刺激)或对单个栅格的适应效果。根据我们的假设，将有一个适应的组成部分，是特定于复合刺激的。在最初的一系列实验中，这两个光栅的取向不同。一块格栅具有最佳取向，另一块格栅与其垂直，因此不会激活研究中的神经元。这些实验为我们的假设提供了支持的证据。在大多数细胞中，对复合刺激的适应减少了对复合刺激的反应，而不是对最佳格栅的反应，对复合刺激的反应比对单个格栅的适应更多地减少了对复合刺激的反应。这表明，适应的一个组成部分是由复合刺激中同时存在的两个方向所特有的(并由其引起的)。为了测试VI神经元是否能够适应刺激属性中的其他偶发事件，我们进行了第二系列实验，其中分量栅格是平行的，但空间频率不同，并且都有效地激活了被研究的神经元。这些实验未能揭示令人信服的适应的偶然效应，这表明神经元不能同样很好地适应所有类型的偶然。
We tested the hypothesis that neurons in the primary visual cortex (VI) adapt selectively to contingencies in the attributes of visual stimuli. We recorded from single neurons in macaque VI and measured the effects of adaptation either to the sum of two gratings (compound stimulus) or to the individual gratings. According to our hypothesis, there would be a component of adaptation that is specific to the compound stimulus. In a first series of experiments, the two gratings differed in orientation. One grating had optimal orientation and the other was orthogonal to it, and therefore did not activate the neuron under study. These experiments provided evidence in favour of our hypothesis. In most cells adaptation to the compound stimulus reduced responses to the compound stimulus more than it reduced responses to the optimal grating, and the responses to the compound stimulus were reduced more by adaptation to the compound stimulus than by adaptation to the individual gratings. This suggests that a component of adaptation was specific to (and caused by) the simultaneous presence of the two orientations in the compound stimulus. To test whether VI neurons could adapt to other contingencies in the stimulus attributes, we performed a second series of experiments, in which the component gratings were parallel but differed in spatial frequency, and were both effective in activating the neuron under study. These experiments failed to reveal convincing contingent effects of adaptation, suggesting that neurons cannot adapt equally well to all types of contingency.