Retrospective analysis of 515 cases of Crohn's disease hospitalization in China: Nationwide study from 1990 to 2003
Retrospective analysis of 515 cases of Crohn's disease hospitalization in China: Nationwide study from 1990 to 2003
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DOI：
10.1111/j.1440-1746.2006.04140.x
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发表时间：
2006-06-01
影响因子：
4.1
通讯作者：
Li, Yanqing
中科院分区：
文献类型：
--
作者：
Ran, Zhihua;Xiao, Shudong;Li, Yanqing
背景资料：目的：了解我国克罗恩病住院情况。方法：对1990-2003年全国22个医疗中心住院克罗恩病的病历进行回顾性分析。每一个事件都由调查人员亲自详细记录在一份定期的综合数据表上。结果：共发现克罗恩病515例，占住院总人数的比例逐年上升。348例（67.57%）患者进行了内镜检查。221例（42.91%）患者接受了钡剂或灌肠治疗。340例（66.02%）患者进行了组织学检查（内镜或手术活检）。435例患者（84.47%）采用了合理的治疗策略。54/303例患者（17.82%）的生活质量的评价是poor.Conclusions：这项回顾性的，以医院为基础的研究表明，克罗恩病在中国的患者人数稳步增加，在一段时间的14年。需要进一步开展以人口为基础的流行病学研究，特别侧重于风险因素。克罗恩病的诊断和治疗策略需要改进。(c)2006 Blackwell Publishing Asia Pty Ltd.
Background: The purpose of the present paper was to investigate the status of Crohn's disease hospitalization in China.methods: Medical records of hospitalized Crohn's disease came from 22 medical centers across China during 1990-2003 and were retrospectively reviewed. Every incident case was recorded in detail on a regular comprehensive datum form by investigators in person. Clinical manifestations, examinations and therapeutic status were analyzed.Results: A total of 515 cases of Crohn's disease were found. The ratio of patients with Crohn's disease to total hospitalized patients has increased steadily year by year. Endoscopy was performed in 348 patients (67.57%). Barium meal or enema was performed in 221 patients (42.91%). Histological examination (endoscopical or surgical biopsy) was performed in 340 patients (66.02%). Reasonable treatment strategies were used for 435 patients (84.47%). The evaluation of quality of life for 54/303 patients (17.82%) was poor.Conclusions: This retrospective, hospital-based study shows that the number of patients with Crohn's disease in China has steadily increased over a period of 14 years. Further population-based epidemiological studies specifically focusing on risk factors are needed. The diagnosis of Crohn's disease and therapeutic strategy require improvement. (c) 2006 Blackwell Publishing Asia Pty Ltd.