Lipodermatosclerosis
Lipodermatosclerosis
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DOI：
10.1111/j.1529-8019.2010.01338.x
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发表时间：
2010-07-01
影响因子：
3.6
通讯作者：
Kirsner, Robert S.
中科院分区：
文献类型：
--
作者：
Miteva, Maria;Romanelli, Paolo;Kirsner, Robert S.
作为最常见的脂性皮炎（LDS）形式，慢性LDS表现为涉及小腿一侧或两侧的皮肤硬结和色素沉着过度，呈特征性的“倒置香槟瓶”外观。与静脉功能不全相关，LDS在中年女性中最常见。除慢性LDS外，也可发生急性形式，常被误诊为蜂窝织炎、炎性硬斑病或结节性红斑。“急性”是指目前的症状是精致的疼痛。LDS的治疗基于临床表现，如果耐受，则将压迫疗法作为治疗的主要手段。对于急性LDS，患者通常由于疼痛而不能耐受加压治疗。我们建议使用纤维蛋白溶解疗法，如果可行的话，直到病人可以忍受压缩袜。
The most commonly recognized form of lipodermatosclerosis (LDS), chronic LDS presents with induration and hyperpigmentation of the skin involving the one or both of the lower legs in a characteristic "inverted champagne bottle" appearance. Associated with venous insufficiency, LDS is most common in middle aged women. In addition to chronic LDS, an acute form may also occur and is often misdiagnosed as cellulitis, inflammatorymorphea, or erythema nodosum. The "acute" refers to the symptoms present that are exquisite pain. Treatment of LDS is based on the clinical presentation with compression therapy as the mainstay of treatment if tolerated. For acute LDS, patients often cannot tolerate compression therapy due to pain. We advise the use of fibrinolytic therapy, if available, until the patient can tolerate compression stockings.