Occurrence of OXA-107 and ISAba1 in Carbapenem-Resistant Isolates of Acinetobacter baumannii from Croatia

Occurrence of OXA-107 and ISAba1 in Carbapenem-Resistant Isolates of Acinetobacter baumannii from Croatia
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DOI:
10.1128/jcm.02394-08
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发表时间:
2009-08
影响因子:
9.4
通讯作者:
--
中科院分区:
医学2区
文献类型:
--
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摘要对克罗地亚斯普利特大学医院重症监护病房分离的碳青霉烯类耐药鲍曼不动杆菌进行了研究。大多数(100/106)的ISAba 1插入blaOXA-107基因上游,编码一种不寻常的OXA-51型苯唑西林酶。脉冲场凝胶电泳显示,分离物形成三个集群属于序列组2(欧洲克隆1)谱系。
ABSTRACT Carbapenem-resistant isolates of Acinetobacter baumannii from intensive care units at Split University Hospital, Split, Croatia, were studied. Most (100 of 106) had ISAba1 inserted upstream of a blaOXA-107 gene, encoding an unusual OXA-51-type oxacillinase. Pulsed-field gel electrophoresis revealed that the isolates formed three clusters belonging to the sequence group 2 (European clone 1) lineage.