THE WISCONSIN EPIDEMIOLOGIC-STUDY OF DIABETIC-RETINOPATHY .3. PREVALENCE AND RISK OF DIABETIC-RETINOPATHY WHEN AGE AT DIAGNOSIS IS 30 OR MORE YEARS
THE WISCONSIN EPIDEMIOLOGIC-STUDY OF DIABETIC-RETINOPATHY .3. PREVALENCE AND RISK OF DIABETIC-RETINOPATHY WHEN AGE AT DIAGNOSIS IS 30 OR MORE YEARS
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DOI：
10.1001/archopht.1984.01040030405011
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发表时间：
1984-01-01
影响因子：
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通讯作者：
DEMETS, DL
中科院分区：
文献类型：
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作者：
KLEIN, R;KLEIN, BEK;DEMETS, DL
在威斯康星州南部（美国）进行的一项基于人群的研究中，对1370名30岁或以上诊断为糖尿病的患者进行了检查，使用标准方案确定糖尿病视网膜病变的患病率和严重程度以及相关的风险变量。糖尿病视网膜病变的患病率从患有糖尿病< 5年的人中的28.8%变化到患有糖尿病≥ 5年的人中的77.8%。15岁增殖性糖尿病视网膜病变的发生率从患有糖尿病< 5年的人中的2.0%变化到患有糖尿病≥ 5年的人中的15.5%。15岁考克斯回归模型显示，视网膜病变的严重程度与糖尿病病程较长、诊断时年龄较小、糖化血红蛋白水平较高、收缩压较高、胰岛素使用、蛋白尿和体重较轻有关。
In a population-based study in southern Wisconsin (USA) 1370 patients given diagnoses of diabetes at age 30 or older were examined using standard protocols to determine the prevalence and severity of diabetic retinopathy and associated risk variables. The prevalence of diabetic retinopathy varied from 28.8% in persons who had diabetes for < 5 yr to 77.8% in persons who had diabetes for .gtoreq. 15 yr. The rate of proliferative diabetic retinopathy varied from 2.0% in persons who had diabetes for < 5 yr to 15.5% in persons who had diabetes for .gtoreq. 15 yr. The Cox regression model showed that the severity of retinopathy was related to longer duration of diabetes, younger age at diagnosis, higher glycosylated Hb levels, higher systolic BP [blood pressure], use of insulin, presence of proteinuria, and small body mass.