Partially overlapping neural networks for real and imagined hand movements
Partially overlapping neural networks for real and imagined hand movements
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DOI：
10.1093/cercor/10.11.1093
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发表时间：
2000-11-01
期刊：
影响因子：
3.7
通讯作者：
Le Bihan, D
中科院分区：
文献类型：
--
作者：
Gerardin, E;Sirigu, A;Le Bihan, D
神经影像学研究结果显示，与想象和运动执行相关的大脑网络相似。另一方面，对顶叶受损患者的神经心理学研究表明，这些网络可能至少部分不同。在本研究中，正常受试者被要求要么想象或执行手势线索的手的动作。与休息时相比，想象和执行表现出重叠的网络，包括双侧运动前区和顶叶区、基底神经节和小脑。然而，两种实验条件之间的直接比较表明，特定的皮质-皮质下区域更多地参与心理模拟，包括双侧运动前区，前额叶，辅助运动区和左后顶叶区，以及尾状核。这些结果表明，一个特定的神经基板参与处理的手运动表征。
Neuroimagery findings have shown similar cerebral networks associated with imagination and execution of a movement. On the other hand, neuropsychological studies of parietal-lesioned patients suggest that these networks may be at least partly distinct. In the present study, normal subjects were asked to either imagine or execute auditory-cued hand movements. Compared with rest, imagination and execution showed overlapping networks, including bilateral premotor and parietal areas, basal ganglia and cerebellum. However, direct comparison between the two experimental conditions showed that specific cortico-subcortical areas were more engaged in mental simulation, including bilateral premotor, prefrontal, supplementary motor and left posterior parietal areas, and the caudate nuclei. These results suggest that a specific neuronal substrate is involved in the processing of hand motor representations.