Corrected human papillomavirus vaccination rates for each birth fiscal year in Japan
Corrected human papillomavirus vaccination rates for each birth fiscal year in Japan
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DOI：
10.1111/cas.14406
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发表时间：
2020-04-27
期刊：
影响因子：
5.7
通讯作者：
Kimura, Tadashi
中科院分区：
文献类型：
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作者：
Nakagawa, Satoshi;Ueda, Yutaka;Kimura, Tadashi
在日本，人乳头瘤病毒（HPV）疫苗接种后的严重不良事件被媒体广泛报道。日本厚生劳动省（MHLW）于2013年宣布暂停HPV疫苗的政府推荐，此后接种率急剧下降。厚生省公布的每个出生财政年度（FY）的估计接种率与地方政府调查的每个出生财政年度的实际接种率差异很大。特别是，厚生省理事会认为，2000财政年度出生的女孩的累计接种率高达42.9%。然而，这一估计包含了一个混乱。当政府在2013财政年度宣布暂停这项建议时，2000财政年度出生的女孩年满13岁，这是HPV疫苗接种的目标起始年龄。这一代的疫苗接种率被认为相当低。在本研究中重新计算了这些数字。这项研究表明，真实的接种率仅为14.3%。在2000财政年度或之后出生的女性已被证实暴露于与日本引进HPV疫苗之前相同的宫颈癌风险。
In Japan, the serious adverse events after human papillomavirus (HPV) vaccination were widely reported in the media. The Ministry of Health, Labour and Welfare of Japan (MHLW) announced the suspension of the governmental recommendation of HPV vaccine in 2013, and the inoculation rate has since sharply declined. The estimated inoculation rate for each birth fiscal year (FY) announced by the MHLW and the actual numbers for each birth FY surveyed by local governments were very different. In particular, the cumulative vaccination rate of girls born in FY2000 was regarded to be as high as 42.9% by the Council of the MHLW. However, this estimation included a confusion. When the suspension of the governmental recommendation was announced in FY2013, the girls born in FY2000 turned 13 years old, the targeted starting age of the HPV vaccination. The vaccination rate of this generation is considered to be quite low. The numbers were recalculated in this study. This study revealed that the real vaccination rate is only 14.3%. Female individuals born in or after FY2000 have been confirmed to be exposed to the same cervical cancer risk as before the HPV vaccine was introduced in Japan.