Tolerance: one transplant for life.
Tolerance: one transplant for life.
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DOI：
10.1097/tp.0000000000000260
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发表时间：
2014-07-27
期刊：
影响因子：
6.2
通讯作者：
Wood KJ
中科院分区：
文献类型：
--
作者：
Kawai T;Leventhal J;Madsen JC;Strober S;Turka LA;Wood KJ
最近召开的 TTS 研讨会旨在解决以下问题：“我们需要采取什么措施才能使耐受诱导方案成为未来十年器官移植受者的“护理标准”？”在为期两天的富有成效的会议上，对一系列广泛的主题进行了广泛的讨论，产生了五项共识建议： 为参加耐受性试验的患者建立结果登记册；建立样本采集和储存的标准化协议；建立标准化的生物标志物和检测方法；将 12 岁及以上儿童纳入已在成人中验证的方案中； (5) 一个工作组，让第三方付款人参与讨论如何资助耐受性试验。未来计划的研讨会将重点讨论实施这些建议的进展情况并确定社区需要采取的其他步骤。
A recent TTS workshop was convened to address the question: “What do we need to have in place to make tolerance induction protocols a “standard of care” for organ transplant recipients over the next decade?” In a productive two day meeting there was wide-ranging discussion on a broad series of topics resulting in five consensus recommendations: Establish a registry of results for patients enrolled in tolerance trials; Establish standardized protocols for sample collection and storage; Establish standardized biomarkers and assays; Include children aged 12 and older in protocols that have been validated in adults; (5) a task force to engage third party payers in discussions of how to fund tolerance trials. Future planned workshops will focus on progress in implementing these recommendations and identifying other steps that the community needs to take.