A pilot trial of the peer-based distribution of HIV self-test kits among fishermen in Bulisa, Uganda.
A pilot trial of the peer-based distribution of HIV self-test kits among fishermen in Bulisa, Uganda.
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DOI：
10.1371/journal.pone.0208191
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Helleringer S
中科院分区：
文献类型：
--
作者：
Choko AT;Nanfuka M;Birungi J;Taasi G;Kisembo P;Helleringer S
艾滋病毒自我检测（HIVST）解决了男性中艾滋病毒诊断的障碍，但目前分发HIVST试剂盒的方法只覆盖了需要检测的男性的一部分。我们在乌干达布利萨区的渔业社区通过同伴网络进行了一项艾滋病毒/艾滋病治疗包二次分发的试点试验。我们在卫生机构的男性患者和社区成员中招募分销商（“种子”）。种子接受了艾滋病毒/艾滋病防治方面的培训，并被要求向其同伴（“新兵”）分发最多五个工具包。使用优惠券将招募者介绍到研究中，并要求返回HIVST试剂盒（使用或未使用）。HIVST的准确性进行了测量对一个卫生工作者进行的验证性测试。我们进行了音频计算机辅助自我访谈，以衡量不良事件的发生，并评估同行提供的HIVST的潜在收益。我们还评估了种子和新兵如何评价他们的经验与同行分布的HIVST。19个种子提供了一个艾滋病毒治疗工具包，116名男子，95（81.9%）接受了报价。没有新兵报告胁迫，但两个种子经历了新兵或他们的家庭成员的敌意。由新兵解释的同伴分布的HIVST的敏感性为100%，特异性为92.8%。在新兵中，29人（25.8%）从未参加过考试，42人（44.2%）在一年多前参加过考试。三名男性艾滋病毒感染者通过同伴分发的艾滋病毒/艾滋病防治试验（产量=每6.3粒种子1个新诊断）了解了自己的状况。大多数新兵（85/88）和种子（19/19）报告说，他们会向朋友和家人推荐艾滋病毒/艾滋病防治技术。所有种子都表示，他们将接受再次担任同行分销商。这种新的基于同伴的HIVST分发模式是安全的，并且具有高吸收率。它可以帮助减少乌干达和其他地方服务不足的渔业社区艾滋病毒检测中的性别差距。
HIV self-testing (HIVST) addresses barriers to HIV diagnosis among men, but current approaches to distributing HIVST kits only reach a subset of the men requiring testing. We conducted a pilot trial of the secondary distribution of HIVST kits through peer networks in fishing communities of Buliisa district (Uganda). We recruited distributors (“seeds”) among male patients of a health facility, and among community members. Seeds were trained in HIVST and asked to distribute up to five kits to their peers (“recruits”). Recruits were referred to the study using a coupon, and asked to return the HIVST kit (used or unused). The accuracy of HIVST was measured against a confirmatory test conducted by a health worker. We conducted audio computer assisted self-interviews to measure the occurrence of adverse events, and evaluate the potential yield of peer-delivered HIVST. We also assessed how seeds and recruits rated their experience with peer-distributed HIVST. Nineteen seeds offered an HIVST kit to 116 men, and 95 (81.9%) accepted the offer. No recruit reported coercion, but two seeds experienced hostility from recruits or their family members. The sensitivity of peer-distributed HIVST, as interpreted by recruits, was 100%, and its specificity was 92.8%. Among recruits, 29 had never tested (25.8%), and 42 (44.2%) had tested more than a year ago. Three men living with HIV learned their status through peer-distributed HIVST (yield = 1 new diagnosis per 6.3 seeds). Most recruits (85/88) and seeds (19/19) reported that they would recommend HIVST to their friends and family. All seeds stated that they would accept acting as peer distributors again. This novel peer-based distribution model of HIVST is safe, and has high uptake. It could help reduce the gender gap in HIV testing in under-served fishing communities in Uganda and elsewhere.
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影响因子：
4.4
作者：
Helleringer, Stephane;Mkandawire, James;Reniers, Georges;Kalilani-Phiri, Linda;Kohler, Hans-Peter
通讯作者：
Kohler, Hans-Peter
影响因子：
15.8
作者：
Masters SH;Agot K;Obonyo B;Napierala Mavedzenge S;Maman S;Thirumurthy H
通讯作者：
Thirumurthy H
影响因子：
3.5
作者：
Mensch, BS;Hewett, PC;Erulkar, AS
通讯作者：
Erulkar, AS
影响因子：
3.7
作者：
Burke VM;Nakyanjo N;Ddaaki W;Payne C;Hutchinson N;Wawer MJ;Nalugoda F;Kennedy CE
通讯作者：
Kennedy CE
DOI：
10.1016/s2352-3018(16)00041-2
发表时间：
2016-06
期刊：
The lancet. HIV
影响因子：
--
作者：
Thirumurthy H;Masters SH;Mavedzenge SN;Maman S;Omanga E;Agot K
通讯作者：
Agot K