Severity of obstructive sleep apnea between black and white patients.
Severity of obstructive sleep apnea between black and white patients.
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DOI：
10.3810/hp.2011.10.926
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发表时间：
2011-10-01
影响因子：
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通讯作者：
Bohnam, Aaron J
中科院分区：
文献类型：
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作者：
Alkhazna, Ammar;Bhat, Abid;Bohnam, Aaron J
阻塞性睡眠呼吸暂停(OSA)是一种相对常见的问题，具有潜在的严重健康后果。本研究的目的是确定种族是否对阻塞性睡眠呼吸暂停综合征的严重程度有任何影响。我们的假设是，当出现OSA时，黑人患者的OSA比白人患者更严重。这项横断面研究是在密苏里大学堪萨斯城医学院附属的教学医院杜鲁门医学中心进行的。进行多元线性回归分析，以确定在控制年龄、性别和体重指数时，种族是否可以预测呼吸暂停低通气指数(AHI)评分。这项分析包括280名拥有模型中每个变量的完整数据的患者。种族(感兴趣的主要预测因素)不能显著预测AHI评分(P=0.172)，年龄也不能(P=0.783)预测AHI评分。男性的AHI评分高于女性(P<；0.001)，体重指数越高，AHI评分越高(P<；0.001)。样本人群中黑人女性多于白人女性(P=0.043)。黑人患者也更有可能患有高血压(P=0.037)。这项研究表明，在控制了年龄、性别和体重指数后，种族不是阻塞性睡眠呼吸暂停严重程度的预测因子。有必要进行更多的研究，以检查不同种族OSA的患病率。
Obstructive sleep apnea (OSA) is a relatively common problem with potentially serious health consequences. The purpose of this study was to identify whether race has any effect on the severity of OSA. Our hypothesis was that OSA, when present, is more severe in black patients than white patients. This cross-sectional study was performed at Truman Medical Centers, a teaching hospital affiliated with University of Missouri-Kansas City School of Medicine (Kansas City, MO). Multiple linear regression analysis was conducted to establish if race was predictive of apnea-hypopnea index (AHI) score when controlling for age, sex, and body mass index. The analysis included 280 patients with complete data for each of the variables in the model. Race (the primary predictor of interest) did not significantly predict AHI score (P = 0.172), and neither did age (P = 0.783). Men had higher AHI scores than women (P < 0.001), and higher body mass index was associated with higher AHI score (P < 0.001). There were more black women in the sample population than white women (P = 0.043). Black patients were also more likely to have hypertension (P = 0.037). This study suggests that race is not a predictor of OSA severity after controlling for age, sex, and body mass index. There is a need for more studies to examine the prevalence of OSA in different races.