Corneal Power Is Correlated with Anterior Chamber Diameter
Corneal Power Is Correlated with Anterior Chamber Diameter
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DOI：
10.1167/iovs.11-8949
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发表时间：
2012-06-01
影响因子：
4.4
通讯作者：
Stell, William K.
中科院分区：
文献类型：
--
作者：
Iribarren, Rafael;Fuentes Bonthoux, Fernando;Stell, William K.
目的.虽然已知角膜屈光力和眼轴长度呈负相关，但角膜屈光力的生物学决定因素尚不清楚。为了进一步阐明这种相关性，研究作者调查了成人样本中角膜屈光力、角膜直径、前房直径和眼轴长度之间的关系。使用高分辨率最佳相干断层扫描（OCT）角膜厚度测量设备和眼科光学生物计对眼科诊所连续观察的61例受试者的眼睛进行了研究。角膜屈光力、白-白白色（WTW）角膜直径、前房直径和眼轴长度之间的关系采用Pearson相关性进行评估。61例受试者的平均年龄为48.7 ± 19.4岁。角膜屈光力与眼轴长度（r =-0.303，P < 0.01）、WTW角膜直径（r =-0.399，P < 0.001）和前房直径（r =-0.646，P < 0.001）呈负相关。前房直径与眼轴长度呈正相关（r = 0.489，P < 0.001）。较大的前房直径与较平坦的角膜相关，相反，较小的前房直径与较陡峭的角膜相关。前节的生长模式可能是角膜屈光力的决定因素。（Invest Ophthalmol维斯科学。2012;53：3788-3791）DOI：10.1167/iovs.11-8949
PURPOSE. Although corneal power and axial length are known to be inversely correlated, the biological determinants of corneal power are unknown. To elucidate this correlation further, study authors investigated the relationships among corneal power, corneal diameter, anterior chamber diameter, and axial length in a sample of human adults.METHODS. The eyes of 61 subjects seen consecutively in an eye clinic were studied with a high-resolution optimal coherence tomography (OCT) pachymetry device and ophthalmic optical biometer. The relationships between corneal power, white-to-white (WTW) corneal diameter, anterior chamber diameter, and axial length were assessed with Pearson correlations.RESULTS. The mean age of the 61 subjects was 48.7 +/- 19.4 years. Corneal power was negatively correlated with axial length (r = -0.303, P < 0.01); WTW corneal diameter (r = -0.399, P < 0.001); and most interestingly, anterior chamber diameter (r = -0.646, P < 0.001). There was also a positive correlation between anterior chamber diameter and axial length (r = 0.489, P < 0.001).CONCLUSIONS. Greater anterior chamber diameters were associated with flatter corneas and, conversely, smaller anterior chamber diameters with steeper corneas. The growth patterns of the anterior segment may be determinants of corneal power. (Invest Ophthalmol Vis Sci. 2012;53:3788-3791) DOI: 10.1167/iovs.11-8949