Efficacy of Electroacupuncture on Treating Depression-Related Insomnia: A Randomized Controlled Trial

Efficacy of Electroacupuncture on Treating Depression-Related Insomnia: A Randomized Controlled Trial
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DOI:
10.2147/nss.s253320
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发表时间:
2020-01-01
影响因子:
3.4
通讯作者:
Xu, Shifen
Xu, Shifen
中科院分区:
医学3区
文献类型:
--
作者:
Yin, Xuan;Li, Wei;Xu, Shifen

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Objective: To evaluate the efficacy of electroacupuncture (EA) on treating insomnia in patients with depression.Patients and Methods: In a patient-assessor-blind, randomized and sham controlled trial, 90 depression patients with insomnia were assigned into three different groups, receiving EA in the treatment group, superficial acupuncture at sham points in the control group A, or Streitberger non-insertion sham acupuncture in the control group B. Treatment was applied 3 times weekly for 8 consecutive weeks. The primary outcome was measured using the Pittsburgh Sleep Quality Index (PSQI). Secondary outcomes were sleep parameters including sleep efficiency (SE), total sleep time (TST) and numbers of sleep awakenings (SA) recorded in the actigraphy, as well as applying the Hamilton Rating Scale for Depression (HAMD-17), Self-Rating Depression Scale (SDS) and Hamilton Rating Scale for Anxiety (HAMA). Assessments were performed at the baseline (week 0), week 4, week 8, and week 12. Linear mixed-effects models were used for analyses and all statistical tests were two-sided.Results: Patients in the EA group had more significant improvement in PSQI scores than those in the control groups over time (respectively p