EFFECT OF BODY POSTURE ON RESPIRATORY IMPEDANCE
EFFECT OF BODY POSTURE ON RESPIRATORY IMPEDANCE
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DOI：
10.1152/jappl.1988.64.1.194
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发表时间：
1988-01-01
影响因子：
3.3
通讯作者：
SANCHIS, J
中科院分区：
文献类型：
--
作者：
NAVAJAS, D;FARRE, R;SANCHIS, J
体位对呼吸系统力学的影响还不是很清楚，特别是在总呼吸阻力方面。用强迫随机噪声激励技术测量了24例健康人坐位和仰卧位的呼吸阻抗(ZRS)。同时测量两种体位的肺活量和肺容量(氦气稀释法)。通过将测得的等效电阻(RRS)、柔度(CRS)和惯性(IRS)拟合到线性序列模型中，还计算出了等效电阻(RRS)、柔度(CRS)和惯性(IRS)。当受试者从坐姿变为仰卧位时，ZRS的实部在整个频段都有所增加。相关的等效电阻RRS增加了28.2%。当频率低于18赫兹时，电抗减小，频率较高时，电抗增大。因此，CRS下降了38.7%，IRS增加了15.6%。所有这些参数差异均有统计学意义(P<；0.001)。协方差分析表明，RRS和CRS的大量姿势变化可以用功能残存容量(FRC)的减少来解释。这表明，ZRs上观察到的差异可以部分解释为FRC的减少导致呼吸系统操作点的移动。
The effects of posture on the mechanics of the respiratory system are not well known, particular in terms of total respiratory resistance. We have measured respiratory impedance (Zrs) by the forced random noise excitation technique in the sitting and the supine position in 24 healthy subjects. Spirometry and lung volumes (He-dilution technique) were also measured in both postures. The equivalent resistance (Rrs), compliance (Crs), and inertance (Irs) were also calculated by fitting each measured Zrs to a linear series model. When subjects changed from sitting to the supine position, the real part of Zrs increased over the whole frequency band. The associated equivalent resistance, Rrs, increased by 28.2%. The reactance decreased for frequencies lower than 18 Hz and increased for higher frequencies. Consequently, Crs decreased by 38.7% and Irs increased by 15.6%. All of these parameter differences were significant (P < 0.001). A covariance analysis showed that a significant amount of the postural change in Rrs and Crs can be explained by the reduction of functional residual capacity (FRC). This indicates that the observed differences on Zrs can in part be explained be a shift of the operating point of the respiratory system induced by the decrease in the FRC.