COVID-19 in patients with HIV-1 infection: a single-centre experience in northern Italy

COVID-19 in patients with HIV-1 infection: a single-centre experience in northern Italy
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DOI:
10.1007/s15010-020-01492-7
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发表时间:
2020-08-03
期刊:
影响因子:
7.5
通讯作者:
Attard, Luciano
Attard, Luciano
中科院分区:
医学3区
文献类型:
--
作者:
Calza, Leonardo;Bon, Isabella;Attard, Luciano

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背景自2020年2月底以来,2019年冠状病毒病(COVID-19)疫情在意大利及其他欧洲国家迅速蔓延,但有关其在艾滋病毒感染患者中的特征的信息有限。方法我们描述了2020年3月和4月期间在S.Orsola医院(意大利博洛尼亚)诊断的HIV感染和COVID-19患者的病例系列。结果我们报告了26例感染COVID-19的HIV感染患者的病例系列。19例受试者为男性,中位年龄为54岁,73%的患者患有一种或多种合并症。仅5例间质性肺炎患者住院,但无重症监护室入院,无死亡病例。结论根据我们的经验,COVID-19与HIV感染相关的临床表现与一般人群相当,并且经常与慢性合并症相关。
Background Since the end of February 2020, the Coronavirus Disease 2019 (COVID-19) outbreak rapidly spread throughout Italy and other European countries, but limited information has been available about its characteristics in HIV-infected patients. Methods We have described a case series of patients with HIV infection and COVID-19 diagnosed at the S.Orsola Hospital (Bologna, Italy) during March and April, 2020. Results We reported a case series of 26 HIV-infected patients with COVID-19. Nineteen subjects were men, the median age was 54 years, 73% of patients had one or more comorbidities. Only 5 patients with interstitial pneumonia were hospitalized, but there were no admissions to intensive care unit and no deaths. Conclusions In our experience, COVID-19 associated with HIV infection had a clinical presentation comparable to the general population and was frequently associated with chronic comorbidities.