Cancer-Related Fatigue and Its Impact on Functioning
Cancer-Related Fatigue and Its Impact on Functioning
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DOI：
10.1002/cncr.28058
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发表时间：
2013-06-01
期刊：
影响因子：
6.2
通讯作者：
Stone, Patrick C.
中科院分区：
文献类型：
--
作者：
Minton, Ollie;Berger, Ann;Stone, Patrick C.
本文介绍了欧洲和美国在癌症相关疲劳（CRF）及其对癌症幸存者功能的影响方面的不同观点。内容分为三个部分：现状、干预研究和未来研究领域，然后是讨论。已确定的差距包括对CRF的病因、定义和测量缺乏了解。需要模型来指导CRF的研究、生物标志物的选择和干预措施的设计。欧洲和美国在CRF研究和合作的未来方向上存在重叠。作者建议，需要就癌症幸存者CRF的定义特征达成国际共识，以确定表型，使用已证明跨语言和文化测量等效的工具对CRF结果进行统一测量，以及手动干预（包括运动，康复和心理教育），以允许不同背景下的干预保真度。洲际间的协调努力将增加对慢性心力衰竭的生物学、心理学和社会机制的理解，并有助于设计未来的干预研究和修订临床指南。(C) 2013年美国癌症协会。
This article presents the contrasting European and American perspectives on cancer-related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There is overlap between Europe and the United States concerning the future directions for research and collaboration related to CRF. The authors suggest the need for international consensus regarding the defining features of CRF in cancer survivors to identify phenotypes, a harmonized measurement of CRF outcomes using instruments that have demonstrated measurement equivalence across languages and cultures, and interventions (including exercise, rehabilitation, and psychoeducational) that have been manualized to permit intervention fidelity across diverse contexts. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying CRF and assist in the design of future intervention studies as well as revisions to clinical guidelines. (C) 2013 American Cancer Society.