Impact of different levels of carbohydrate intolerance on neonatal outcomes classically associated with gestational diabetes mellitus
Impact of different levels of carbohydrate intolerance on neonatal outcomes classically associated with gestational diabetes mellitus
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DOI：
10.1016/s0301-2115(01)00575-9
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发表时间：
2002-04-10
期刊：
影响因子：
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通讯作者：
Gálvez-Vargas, R
中科院分区：
文献类型：
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作者：
Jiménez-Moleón, JJ;Bueno-Cavanillas, A;Gálvez-Vargas, R
目的：比较不同程度糖耐量异常对新生儿结局的影响。螺柱，V型设计：对1995年在西班牙格拉纳达大学医院分娩的1962例妊娠期糖尿病筛查孕妇进行回顾性随访。将孕妇分为3组：诊断为妊娠期糖尿病组、筛查阳性但未诊断妊娠期糖尿病组。负屏幕。对各组新生儿不良结局的频率进行量化，并比较其统计学意义。结果：妊娠糖尿病与高出生体重、低血糖和低钙血症的发生率相关。对疾病进行充分的代谢控制可降低不良结局的风险。出生体重与碳水化合物不耐受程度呈正斜率。无论是否存在碳水化合物不耐受，有妊娠期糖尿病危险因素的孕妇中巨大儿的发生率总是高于无妊娠期糖尿病危险因素的孕妇。结论：孕妇妊娠期糖尿病危险因素和孕妇更大的碳水化合物不耐受与不良新生儿结局的增加相关。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
Objective: To compare the influence of different levels of carbohydrate intolerance on neonatal outcomes. Stud,v design: The cohort constituted by the 1962 pregnant women screened for gestational diabetes who gave birth at the University Hospital of Granada (Spain) in the year 1995 was followed retrospectively, Women were classified into three groups: diagnosis of gestational diabetes, positive screen but non-gestational diabetes. and negative screen. Frequency of adverse newborn outcomes were quantified for each group and compared for statistical significance. Results: Gestational diabetes was associated with a greater incidence of high birth weight, hypoglycemia and hypocalcemia. Adequate metabolic control of the illness reduced the risk of adverse outcomes. Birth weight traced a positive slope with respect to the degree of carbohydrate intolerance. Regardless of carbohydrate intolerance, macrosomia was always higher among gravidae with gestational diabetes risk factors than among women without them. Conclusion: Both maternal gestational diabetes risk factors and greater carbohydrate intolerance in gravidae are associated with an increase in adverse newborn outcomes. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.