QTLs associated with resistance to soybean cyst nematode in soybean: Meta-analysis of QTL locations
QTLs associated with resistance to soybean cyst nematode in soybean: Meta-analysis of QTL locations
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DOI：
10.2135/cropsci2005.04-0036-2
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发表时间：
2006-03-01
期刊：
影响因子：
2.3
通讯作者：
Arelli, PR
中科院分区：
文献类型：
--
作者：
Guo, B;Sleper, DA;Arelli, PR
大豆胞囊线虫（Heterodera glycines Ichinohe）是大豆[Glycine max（L.）梅尔。]世界上迄今为止，已有17篇大豆抗胞囊线虫QTL定位报告和62个标记-QTL关联分析。经常出现不合格的结果。本研究的目的是：（i）评估已报道的大豆SCN抗性标记-QTL关联的证据;（ii）从已报道的大豆SCN抗性标记-QTL关联中提取相对可靠和有用的信息。通过比较所报道的QTL的95%置信区间，对QTL位置进行荟萃分析。如果不同品种或不同研究的QTL的置信区间有一个共同的区域，则将其聚为一个簇。同一聚类的QTL可能有一个共同的位点。如果不同品种或不同研究的QTL的置信区间没有共同区域，且彼此之间的距离大于等于20 cM，则可将其归为不同的类群。不同的簇可以代表不同的基因座。已报道的抗SCN QTL可分为3类：提示性、显著性和已证实的。已确定的QTL是可靠的，可作为精细定位和基因克隆的候选位点。连锁群G、A2、B1、E和J上的QTL被归类为确定的。在LG G上定位到两个QTL簇。其中之一是rhg 1。在LG B1的末端附近检测到一簇QTL，而在LG B1的中部附近可能存在一个QTL。在LGS A2、E和J上分别定位到一个QTL簇。在LGS B2、C1、C2、D1 a、D2、L、M和N上的QTL被分为提示性和显著性两类。这些QTL的可信度还需要进一步的验证研究。讨论了大豆SCN小种与QTL的关系。
Soybean cyst nematode (SCN) (Heterodera glycines Ichinohe) is the most important pest of soybean [Glycine max (L.) Merr.] in the world. A total of 17 quantitative trait locus (QTL) mapping papers and 62 marker-QTL associations have been reported for resistance to soybean cyst nematode in soybean. Conflicting results often occurred. The objectives of this study were to: (i) evaluate evidence for reported marker-QTL associations for resistance to SCN in soybean and (ii) extract relatively reliable and useful information from the reported marker-QTL associations in soybean. A meta-analysis was conducted for QTL locations by comparing the 95% confidence intervals of the reported QTLs. QTLs for different races or different studies were classified into one cluster if their confidence intervals had a region in common. The QTLs of the same cluster may have a shared locus. QTLs for different races or different studies were classified into different clusters if their confidence regions had no region in common and were >= 20 cM away from each other. Different clusters may represent different loci. Reported SCN resistant QTLs were classified into three categories: suggestive, significant, and confirmed. Confirmed QTLs are credible and can be candidates for fine mapping and gene cloning. QTLs on linkage groups (LGs) G, A2, B1, E, and J were classified as confirmed. Two clusters of QTLs were identified on LG G. One of them is rhg1. One cluster of QTLs was identified near the end of LG B1, but one QTL may exist around the middle of LG B1. One cluster of QTLs was identified on LGs A2, E, and J, respectively. QTLs on LGs B2, C1, C2, D1a, D2, L, M, and N were classified into suggestive or significant. Confirmation studies are needed to lend credibility for these QTLs. A relationship between soybean QTLs and SCN races is discussed.