Krebs Cycle Rewired: Driver of Atherosclerosis Progression?
Krebs Cycle Rewired: Driver of Atherosclerosis Progression?
复制标题
DOI：
10.2174/0929867328666210806105246
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Dangheng Wei
中科院分区：
文献类型：
--
作者：
Yamin Liang;Yanmei Chen;Lu Li;Shulei Zhang;Jinyan Xiao;Dangheng Wei
:.The tricarboxylic acid (TCA) cycle is the center of energy metabolism in eukaryotic.cells and is dynamically adjusted according to the energy needs of cells. Macrophages.are activated by inflammatory stimuli, and then two breakpoints in TCA cycle lead to the.accumulation of intermediates. Atherosclerosis is a chronic inflammatory process. Here, the."non-metabolic" signaling functions of TCA cycle intermediates in the macrophage under.inflammatory stimulation and the role of intermediates in the progression of atherosclerosis.are discussed.
