Evolution and prophylaxis of human rabies
Evolution and prophylaxis of human rabies
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DOI：
10.1590/s1678-91992005000100003
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发表时间：
2005-03-01
影响因子：
2.4
通讯作者：
Barraviera, B.
中科院分区：
文献类型：
--
作者：
Ayres, J.A.;Peraçoli, M. T. S.;Barraviera, B.
狂犬病是一种进行性和致命性的病毒性急性脑炎，特别是在热血动物身上，并意外影响男性。由于它是一种不同动物种类的人畜共患病，在自然界中起着蓄水池的作用，在一些正在发展中的国家，这种疾病是一个严重的公共卫生问题。人类狂犬病的预防性治疗始于1885年的路易斯·巴斯德，发展起来是为了提供更高的保护和更低的副作用发生率。今天，暴露在病毒前和暴露后的治疗方法已经确立，对接触可能被狂犬病病毒污染的动物的个人具有良好的保护效果。这些治疗包括单独或与马免疫球蛋白联合使用疫苗，这在很大程度上有助于减少狂犬病病例的数量。
Rabies is a viral acute encephalitis of progressive and fatal outcome, particular of hot-blooded animals, and accidentally affecting men. Since it is a zoonosis with different animal species acting as a reservoir in the nature, this disease is a great public health problem in several countries in development. Prophylactic treatments for human rabies started in 1885 with Louis Pasteur, and developed in order to provide higher protection and lower incidence of side effects. Today, treatments of pre and post-exposure to the virus are well established, with excellent results of protection for individuals exposed to animals potentially contaminated by the rabies virus. These treatments consist of utilising the vaccine isolatedly or in combination with equine immunoglobulin, what contributes, in an important way, to the decrease in the number of cases of rabies.