Low-Level Lasers as an Adjunct in Periodontal Therapy in Patients with Diabetes Mellitus
Low-Level Lasers as an Adjunct in Periodontal Therapy in Patients with Diabetes Mellitus
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DOI：
10.1089/dia.2012.0027
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发表时间：
2012-09-01
影响因子：
5.4
通讯作者：
Brkic, Zlata
中科院分区：
文献类型：
--
作者：
Obradovic, Radmila;Kesic, Ljiljana;Brkic, Zlata
背景：糖尿病（diabetes mellitus，DM）增加了牙周炎的发病风险，重度牙周炎常与重度DM并存。提出的组织破坏的双重途径表明，控制慢性牙周感染和牙龈炎症是实现长期控制糖尿病的关键。本研究的目的是评估低强度激光治疗（LLLT）的影响，脱落细胞学在患者DM和牙龈inflations.Subjects和方法：300例患者分为三个相等的组：组1的患者牙周炎和1型DM，组2的患者牙周炎和2型DM，组3的患者牙周炎（对照组）。口腔检查后，从牙龈组织中提取涂片，然后所有患者接受口腔卫生指导，去除牙菌斑，全口洁治和根面平整。应用裂口设计;在钳口右侧应用GaAlAs LLLT（670 nm，5 mW，14 min/天）（型号Mils 94; Optica Laser，索菲亚，保加利亚），连续5天。治疗完成后，从两侧颌骨采集涂片。使用美国国立卫生研究院图像软件程序和NU 2型显微镜（Carl Zeiss，Jena，德国）进行形态计量学分析。治疗后的一方受到LLLT，有DM和对照组之间没有显着差异。结论：可以得出结论，LLLT作为牙周治疗的辅助减少牙龈炎症的患者与DM和牙周炎。
Background: Diabetes mellitus (DM) increases the risk of periodontitis, and severe periodontitis often coexists with severe DM. The proposed dual pathway of tissue destruction suggests that control of chronic periodontal infection and gingival inflammation is essential for achieving long-term control of DM. The purpose this study is to evaluate the effects of low-level laser therapy (LLLT) by exfoliative cytology in patients with DM and gingival inflammation.Subjects and Methods: Three hundred patients were divided in three equal groups: Group 1 consisted of patients with periodontitis and type 1 DM, Group 2 of patients with periodontitis and type 2 DM, and Group 3 of patients with periodontitis (control group). After oral examination, smears were taken from gingival tissue, and afterward all of the patients received oral hygiene instructions, removal of dental plaque, and full-mouth scaling and root planing. A split-mouth design was applied; on the right side of jaws GaAlAs LLLT (670 nm, 5 mW, 14 min/day) (model Mils 94; Optica Laser, Sofia, Bulgaria) was applied for five consecutive days. After the therapy was completed, smears from both sides of jaws were taken. The morphometric analysis was done using the National Institutes of Health Image software program and a model NU2 microscope (Carl Zeiss, Jena, Germany).Results: Investigated parameters were significantly lower after therapy compared with values before therapy. After therapy on the side subjected to LLLT, there was no significantly difference between patients with DM and the control group.Conclusions: It can be concluded that LLLT as an adjunct in periodontal therapy reduces gingival inflammation in patients with DM and periodontitis.