Estimation of the following Cardiac Output Using Sympathetic Tone and Hemodynamics for the Control of a Total Artificial Heart
Estimation of the following Cardiac Output Using Sympathetic Tone and Hemodynamics for the Control of a Total Artificial Heart
复制标题
使用交感神经张力和血流动力学估计以下心输出量以控制全人工心脏
DOI：
10.1177/039139889201501007
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
H. Takeda
中科院分区：
文献类型：
--
作者：
T. Yambe;S. Nitta;Y. Katahira;T. Sonobe;S. Naganuma;H. Akiho;Y. Kakinuma;K. Izutzu;Y. Kikuchi;T. Naganuma;S. Kobayashi;H. Matsuzawa;M. Tanaka;M. Miura;N. Sato;T. Fukuju;H. Mohri;M. Yoshizawa;H. Takeda
交感神经图对于实时全人工心脏 (TAH) 控制系统的开发可能有用。我们使用交感张力和血流动力学导数来估计成年杂种狗的急性动物实验中的以下心输出量。平均左心房压力和平均主动脉压力的移动平均值分别用作前负荷和后负荷的参数。肾交感神经活动（RSNA）被用作交感张力的参数。使用时间序列数据的多元线性回归分析计算以下心输出量的方程。在估计的心输出量和随后测量的心输出量之间观察到显着的相关性。这些结果表明交感神经图对于实时 TAH 自动控制系统具有潜在的用途。
A sympathetic neurogram is potentially useful for the development of a real time total artificial heart (TAH) control system. We used sympathetic tone and hemodynamic derivatives to estimate the following cardiac output in acute animal experiments using adult mongrel dogs. Moving averages of the mean left atrial pressure and mean aortic pressure were used as parameters of the preload and afterload, respectively. Renal sympathetic nerve activity (RSNA) was employed as a parameter of sympathetic tone. Equations for the following cardiac output were calculated using multiple linear regression analysis of the time series data. A significant correlation was observed between the estimated and following measured cardiac output. These results suggest the potential usefulness of the sympathetic neurogram for the real time TAH automatic control system.