Vasoconstriction and blood flow responses in visceral arteries to mental task in humans

Vasoconstriction and blood flow responses in visceral arteries to mental task in humans
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DOI:
10.1113/expphysiol.2005.031971
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发表时间:
2006-01-01
影响因子:
2.7
通讯作者:
Fukuba, Y
Fukuba, Y
中科院分区:
医学4区
文献类型:
--
作者:
Hayashi, N;Someya, N;Fukuba, Y

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人类内脏动脉对心理任务的血管反应尚未阐明。应用脉冲多普勒超声和回波多普勒超声同时检测肾动脉(RA)和上级肠系膜动脉(SMA)对精神应激的反应。9名健康女性进行计算机色词冲突试验(CWT)3min,测量右RA和SMA的平均血流速度(MBV)、心率(HR)和血压。用平均动脉压(MAP)除以血流速度来计算血管阻力(VR)。CWT从第1分钟开始显著增加两支动脉的MAP、HR和VR。在CWT期间,相对于基线,RA中的流量在第3分钟显著降低,而SMA中的流量从第1分钟到第3分钟没有显著变化。RA床的血管收缩程度大于SMA床。这些结果表明,心理任务引起内脏动脉血管收缩,并暗示它引起内脏动脉的差异血流和血管反应。
The vascular responses to mental task in visceral arteries in humans have not been elucidated. We observed the responses in the renal (RA) and superior mesenteric (SMA) arteries to mental stress, using simultaneous pulsed and echo Doppler ultrasound flowmetry. Nine healthy females performed a computerized colour word conflict test (CWT) for 3 min. The mean blood velocity (MBV) in the right RA and SMA, heart rate (HR) and blood pressure were measured. The mean arterial pressure (MAP) was divided by the flow velocity to assess the vascular resistance (VR). The CWT significantly increased the MAP, HR and VR in both arteries from the first minute. During the CWT, flow in the RA decreased significantly at the third minute relative to baseline, while flow in the SMA showed no significant change from the first to the third minute. The degree of vasoconstriction in the RA bed was greater than that in the SMA bed. These results suggest that the mental task causes vasoconstriction in visceral arteries, and imply that it induces differential blood flow and vascular responses in visceral arteries.