Knee imaging: Rapid three-dimensional fast spin-echo using compressed sensing.
Knee imaging: Rapid three-dimensional fast spin-echo using compressed sensing.
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DOI：
10.1002/jmri.25507
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发表时间：
2017-06
期刊：
影响因子：
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通讯作者：
Liu F
中科院分区：
文献类型：
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作者：
Kijowski R;Rosas H;Samsonov A;King K;Peters R;Liu F
目的探讨压缩传感(CS)加速膝关节三维快速自旋回波(3D-FSE)成像的可行性。对10名健康志愿者进行3次3D-FSE序列扫描，分别在有CS(3：16分钟扫描时间)和无CS(CUBE扫描时间4：44分钟)的膝关节上进行2次3D-FSE序列扫描，采用加减法测量信噪比(SNR)，并对50例有症状的患者进行1次膝关节3D-FSE序列扫描以评估诊断效果。在CUBE和CUBE-CS图像上测量了10名健康志愿者的软骨、肌肉、滑液和骨髓的信噪比。所有50名有症状的患者的CUBE和CUBE-CS序列都由两名肌肉骨骼放射科医生独立审查了两次。放射科医生在每次个体回顾中使用CUBE和CUBE-CS来确定膝关节病变的存在或缺失。学生t检验用于比较序列之间的SNR值，而Kappa统计量用于确定序列之间用于检测膝关节病理的一致性。在18名有症状的患者中，还计算了CUBE和CUBE-CS检测膝关节病理的敏感性和特异性，这些患者随后接受了膝关节镜手术。CUBE-CS和CUBE-CS的软骨、肌肉、滑液和骨髓的SNR相似(p=0.15-0.67)。对于两位放射科医生来说，CUBE和CUBE-CS在检测软骨和骨髓水肿性损害、内侧和外侧半月板撕裂、前十字韧带撕裂、积液和关节内小体方面几乎完全一致。对于手术证实的60个软骨病变、20个半月板撕裂、4个前交叉韧带撕裂和4个关节内小体，Cube和Cube-CS具有相似的敏感性(75.0%~100%)和特异性(87.5%~100%)。CS使膝关节3D-FSE成像的扫描时间减少了30%，而SNR或诊断性能没有相应的下降。
To investigate the feasibility of using compressed sensing (CS) to accelerate three-dimensional fast spin-echo (3D-FSE) imaging of the knee. A 3D-FSE sequence was performed at 3T with CS (CUBE-CS with 3:16 minute scan time) and without CS (CUBE with 4:44 minute scan time) twice on the knees of 10 healthy volunteers to assess signal-to-noise ratio (SNR) using the addition-subtraction method and once on the knees of 50 symptomatic patients to assess diagnostic performance. SNR of cartilage, muscle, synovial fluid, and bone marrow on CUBE and CUBE-CS images were measured in the 10 healthy volunteers. The CUBE and CUBE-CS sequences of all 50 symptomatic patients were independently reviewed twice by two musculoskeletal radiologists. The radiologists used CUBE and CUBE-CS during each individual review to determine the presence or absence of knee joint pathology. Student t-tests were used to compare SNR values between sequences, while kappa statistic was used to determine agreement between sequences for detecting knee joint pathology. Sensitivity and specificity of Cube and Cube-CS for detecting knee joint pathology was also calculated in the 18 symptomatic patients who underwent subsequent arthroscopic knee surgery. CUBE and CUBE-CS had similar SNR (p=0.15-0.67) of cartilage, muscle, synovial fluid, and bone marrow. There was near perfect to perfect agreement between CUBE and CUBE-CS for both radiologists for detecting cartilage and bone marrow edema lesions, medial and lateral meniscus tears, anterior cruciate ligament tears, effusions, and intra-articular bodies. Cube and Cube-CS had similar sensitivity (75.0%-100%) and specificity (87.5%-100%) for detecting 60 cartilage lesions, 20 meniscus tears, four anterior cruciate ligament tears, and four intra-articular bodies confirmed at surgery. CS provided a 30% reduction in scan time for 3D-FSE imaging of the knee without a corresponding decrease in SNR or diagnostic performance.