Interaction of dopamine and acetylcholine with an amphiphilic resorcinarene receptor in aqueous micelle system
Interaction of dopamine and acetylcholine with an amphiphilic resorcinarene receptor in aqueous micelle system
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DOI：
10.1016/j.bmcl.2005.01.012
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发表时间：
2005-03-01
影响因子：
2.7
通讯作者：
Tóth, K
中科院分区：
文献类型：
--
作者：
Demura, M;Yoshida, T;Tóth, K
在十二烷基硫酸钠（SDS）胶束体系中，用核磁共振氢谱研究了两亲性间苯二酚芳烃受体对神经递质多巴胺和乙酰胆碱的分子识别.这些神经递质从两亲性受体的亲水性腔的相互作用距离估计的基础上的环电流移动的计算，使用从分子动力学计算得到的原子坐标。(c)2005爱思唯尔有限公司保留所有权利。
The molecular recognition of neurotransmitters, dopamine and acetylcholine with an amphiphilic resorcinarene receptor was investigated in an aqueous sodium dodecylsulfate (SDS) micelle system by H-1 NMR measurements. The interaction distances of these neurotransmitters from the hydrophilic cavity of the amphiphilic receptor were estimated based on the calculation of the ring current shift using the atomic coordinates obtained from molecular dynamics calculation. (c) 2005 Elsevier Ltd. All rights reserved.