Burden of liver disease in the United States: Summary of a workshop
Burden of liver disease in the United States: Summary of a workshop
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DOI：
10.1053/jhep.2002.34734
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发表时间：
2002-07-01
期刊：
影响因子：
13.5
通讯作者：
El-Serag, H
中科院分区：
文献类型：
--
作者：
Kim, WR;Brown, RS;El-Serag, H
疾病负担是一个术语，包括疾病对人口健康影响的若干方面，范围从（1）疾病的频率，以发病率和流行率衡量，到其对寿命的影响，如病死率和因过早死亡而损失的寿命，（3）发病率，包括健康状况和生活质量的下降，以及（4）财务，包括直接保健支出和与过早死亡或残疾造成的收入损失有关的间接费用。准确了解肝病负担对于制定卫生保健政策以优先考虑健康干预和研究并相应分配资源至关重要。肝病被认为是相对罕见的。然而，某些肝脏疾病（例如，非酒精性脂肪肝或丙型肝炎）在人群中普遍存在，而其他疾病（例如，肝细胞癌[HCC]或暴发性肝衰竭[FHF]）则具有高度致命性。虽然有效的治疗和预防可用于许多类型的肝脏疾病，持续肝损伤的长期后果可能需要肝移植，其中一个最涉及的医疗enterprisesperformedtoday.This审查代表了一个研讨会的总结由美国肝病研究协会在2001年5月与消化系统疾病周。研讨会的目的是收集关于肝病流行病学和负担的可用数据
Disease burden is a term that encompasses a num-ber of aspects of the impact of a disease on the health of a population, ranging from (1) the frequency of the disease, as measured by incidence and prevalence, to its effect on (2) longevity, such as casefatality rate and years of life lost due to premature death,(3) morbidity including decrease in health status and quality of life, and (4) finance, including direct health care expenditures and indirect costs related to lost income from premature death or disability. Accurate knowledge of the burden of liver disease is essential in formulating health care policies to prioritize health interventions and research and to allocate resources accordingly. Liver disease is thought to be relatively rare. However, some liver diseases (eg, nonalcoholic fatty liver disease or hepatitis C) are prevalent in the population and others (eg, hepatocellular carcinoma [HCC] or fulminant hepatic failure [FHF]) are highly lethal. While effective treatment and prevention are available for many types of liver disease, long-term consequences of ongoing liver damage may necessitate liver transplantation, one of the most involved medical undertakings performed today.This review represents a summary of a workshop conducted by the American Association for the Study of Liver Disease in May 2001 in conjunction with the Digestive Disease Week. The goal of the workshop was to assemble available data on epidemiology and burden of liver disease