The incidence and pathogenesis of acute renal failure following cardiac surgery, and strategies for its prevention.
The incidence and pathogenesis of acute renal failure following cardiac surgery, and strategies for its prevention.
复制标题
心脏手术后急性肾衰竭的发生率、发病机制及其预防策略。
DOI：
10.4103/0971-9784.38777
复制
发表时间：
2004
影响因子：
0.9
通讯作者：
David C. Smith
中科院分区：
文献类型：
--
作者：
K. Yallop;David C. Smith
体外循环（CPB）后肾功能不全导致显著的发病率和死亡率。已经有许多关于减少肾损伤的可能方法的研究，但是许多有希望的实验室工作在临床竞技场中未能达到期望，使得没有广泛接受的心脏手术患者的肾保护策略。部分困难在于，肾功能不全没有标准化的定义，并且有数量有限的高质量随机对照临床试验。
Renal dysfunction following cardiopulmonary bypass (CPB) causes significant morbidity and mortality. There has been much research into possible methods of reducing renal damage, but much promising laboratory work has failed to live up to expectations in the clinical arena, such that there is no widely accepted renal protection strategy for cardiac surgical patients. Part of the difficulty is that there is no standardized definition of renal dysfunction, and there are a limited number of good quality randomised controlled clinical trials.